Computational Analysis of POL Gene of Human Immunodeficiency Virus Type 1 (HIV-1)

被引:0
作者
Behera, Pabitra M. [1 ]
Sethi, Bijay K. [2 ]
Behera, Kambaska K. [2 ]
Pani, Debashrita [2 ]
Sahoo, Santilata [2 ]
Padhy, Sudarshan [1 ]
机构
[1] Utkal Univ, Dept Math Stat & Comp Sci, Bhubaneswar 751004, Orissa, India
[2] Utkal Univ, Dept Appl Microbiol, Bhubaneswar 751004, Orissa, India
关键词
AIDS; HIV-1; POL gene; retrovirus; MULTIPLE SEQUENCE ALIGNMENT; ALGORITHM;
D O I
暂无
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
AIDS results from an infection with HIV-1 virus. It is a class of retrovirus whose genome contains the genes for reverse transcriptase. The gene that codes for reverse transcriptase in HIV-1 is the POL gene. POL genes are found in many retroviruses, including a number that are harbored by human populations. Inch is paper POL genes of HIV-1 virus were studied using bioinformatics tools. It was observed that there exists a close resemblance among various strains endemic in Africa, China and India. In addition, they express a wide range of functional proteins after infection.
引用
收藏
页码:264 / 269
页数:6
相关论文
共 22 条
[1]  
*ACC D S, V1 7 DISC STUD FLEX
[2]  
[Anonymous], Los Angeles Times
[3]  
BROWN P, 1991, NEW SCI 0525
[4]  
*CDCP, MORBIDITY MORTALITY, V30, P250
[5]  
*CDCP, MORBIDITY MORTALITY, V30, P305
[6]  
FelsensteinJ, 1989, PHYLIP (phylogeny inference package) version 3.6, V5, P164
[7]   Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes [J].
Gao, F ;
Bailes, E ;
Robertson, DL ;
Chen, YL ;
Rodenburg, CM ;
Michael, SF ;
Cummins, LB ;
Arthur, LO ;
Peeters, M ;
Shaw, GM ;
Sharp, PM ;
Hahn, BH .
NATURE, 1999, 397 (6718) :436-441
[8]  
*HIV SEQ COMP, 2008, ANN REV
[9]   MOLECULAR RECOGNITION OF RECEPTOR-SITES USING A GENETIC ALGORITHM WITH A DESCRIPTION OF DESOLVATION [J].
JONES, G ;
WILLETT, P ;
GLEN, RC .
JOURNAL OF MOLECULAR BIOLOGY, 1995, 245 (01) :43-53
[10]   Development and validation of a genetic algorithm for flexible docking [J].
Jones, G ;
Willett, P ;
Glen, RC ;
Leach, AR ;
Taylor, R .
JOURNAL OF MOLECULAR BIOLOGY, 1997, 267 (03) :727-748