Shear stress in cells generated by ultrasound

被引：72

作者：

Wu, Junru ^{[1
]}

机构：

[1] Univ Vermont, Dept Phys, Burlington, VT 05405 USA

来源：

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY | 2007年 / 93卷 / 1-3期

关键词：

ultrasound; ultrasound imaging; contrast agents; microstreaming; shear stress;

D O I：

10.1016/j.pbiomolbio.2006.07.016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An experimental study using a mason horn of 21.4 kHz indicated that the threshold shear stress for cell sonoporation was 12 +/- 4 Pa for ultrasound exposure time up to 7 min. Numerical calculations have shown that shear stress associated with microstreaming surrounding encapsulated bubbles may be large enough to generate sono poration at 0.1 MPa of 1 or 2 MHz ultrasound. (c) 2006 Published by Elsevier Ltd.

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收藏

页码：363 / 373

页数：11

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