Synthesis of Pyrroles by Gold(I)-Catalyzed Amino-Claisen Rearrangement of N-Propargyl Enaminone Derivatives

被引：236
作者：
Saito, Akio [1 ]
Konishi, Tomoyo [1 ]
Hanzawa, Yuji [1 ]
机构：
[1] Showa Pharmaceut Univ, Lab Organ React Chem, Tokyo 1948543, Japan
来源：
ORGANIC LETTERS | 2010年 / 12卷 / 02期
关键词：
SUBSTITUTED PYRROLES; EFFICIENT SYNTHESIS; 2-PROPYNYL-1,3-DICARBONYL COMPOUNDS; AMINATION/ANNULATION REACTIONS; REGIOSELECTIVE SYNTHESIS; BIOLOGICAL-ACTIVITY; CATALYZED REACTION; CYCLOISOMERIZATION; HETEROCYCLES; CYCLIZATION;
D O I：
10.1021/ol902716n
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The cationic N-heterocyclic carbene-gold(I) complex catalyzes the formation of tri- and tetrasubstituted pyrroles via the amino-Claisen rearrangement of N-propargyl beta-enaminone derivatives and the cyclization of alpha-allenyl beta-enaminone Intermediates.
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收藏
页码：372 / 374
页数：3
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