The incidence of toxic shock syndrome due to nosocomial methicillin-resistant Staphylococcus aureus infection in burn patients: A four-year retrospective cohort study

被引：5

作者：

Matsushima, Asako ^{[1
]}

Kuroki, Yuichi ^{[2
]}

Nakajima, Shinji ^{[2
]}

Kojima, Hiroki ^{[3
]}

Seki, Tadahiko ^{[4
]}

Ueyama, Masashi ^{[2
]}

机构：

[1] Nagoya City Univ, Grad Sch Med Sci, Dept Adv Acute Med, Mizuho Ku, 1 Kawasumi,Mizuho Cho, Nagoya, Aichi 4678602, Japan

[2] Japan Community Hlth Care Org, Chukyo Hosp, Dept Trauma, Crit Care Med & Burn Ctr, 1-1-10 Sanjo, Nagoya, Aichi 4578510, Japan

[3] Aichi Med Univ Hosp, 1-1 Iwasakukarimata, Nagakute, Aichi 4801195, Japan

[4] Nara Prefecture Gen Med Ctr, Dept Emergency & Crit Care Med, 1-30-1 Hiramatsu, Nara, Nara 6310846, Japan

来源：

BURNS | 2021年 / 47卷 / 02期

关键词：

Burn; Methicillin-resistant; Staphylococcus aureus; Nosocomial infection; Sepsis; Toxic shock syndrome;

D O I：

10.1016/j.burns.2020.07.005

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Among adult and pediatric patients, concern is growing in regard to toxic shock syndrome (TSS) resulting from methicillin-resistant Staphylococcus aureus (MRSA) nosocomial infection. We investigated the incidence and characteristics of this form of TSS in patients with burn injury who were admitted to our burn care units from January 2008 to December 2011. Of the 244 patients with nosocomial MRSA infection admitted during the study period, TSS occurred in 20 (8.2%) patients whose average age was 42.9 years, average total burn surface area (TBSA) was 31.7%, and average day of TSS appearance was 9.5 days after injury. There were no particular characteristics associated with age, TBSA or day of TSS appearance in these patients. All but 1 patient recovered from TSS within an average of 9.4 days. The incidence of TSS due to nosocomial MRSA infection in these burn patients was higher than expected. TSS due to nosocomial MRSA infection should be considered in burn care. (c) 2020 Elsevier Ltd and ISBI. All rights reserved.

引用

页码：402 / 407

页数：6

共 14 条

[1] Bacterial toxicosis/toxic shock syndrome as a contributor to morbidity in children with burn injuries [J].

Brown, AP ;

Khan, K ;

Sinclair, S .

BURNS, 2003, 29 (07) :733-738

[2]

Centers for Disease Control and Prevention, TOX SHOCK SYNDR OTH

[3] Staphylococcal Toxic Shock Syndrome 2000-2006: Epidemiology, Clinical Features, and Molecular Characteristics [J].

DeVries, Aaron S. ;

Lesher, Lindsey ;

Schlievert, Patrick M. ;

Rogers, Tyson ;

Villaume, Lourdes G. ;

Danila, Richard ;

Lynfield, Ruth .

PLOS ONE, 2011, 6 (08)

[4] A survey into toxic shock syndrome (TSS) in UK burns units [J].

Edwards-Jones, V ;

Dawson, MM ;

Childs, C .

BURNS, 2000, 26 (04) :323-333

[5]

Fujimori S, 2001, KEISEIGEKA, V44, P271

[6]

Lakhundi S, 2018, CLIN MICROBIOL REV, V31, DOI [10.1128/CMR.00020-18, 10.1128/cmr.00020-18]

[7] Low Level of TSST-1 Antibody in Burn Patients With Toxic Shock Syndrome Caused by Methicillin-Resistant Staphylococcus aureus [J].

Matsushima, Asako ;

Kuroki, Yuich ;

Nakajima, Shinji ;

Sakai, Tomohiko ;

Kojima, Hiroki ;

Ueyama, Masashi .

JOURNAL OF BURN CARE & RESEARCH, 2015, 36 (03) :E120-E124

[8] Prevalence of toxic shock syndrome toxin 1 (TSST-1)-producing strains of Staphylococcus aureus and antibody to TSST-1 among healthy Japanese women [J].

Parsonnet, Jeffrey ;

Goering, Richard V. ;

Hansmann, Melanie A. ;

Jones, Michaelle B. ;

Ohtagaki, Kumiko ;

Davis, Catherine C. ;

Totsuka, Kyoichi .

JOURNAL OF CLINICAL MICROBIOLOGY, 2008, 46 (08) :2731-2738

[9] Toxic shock syndrome toxin-1 (TSST-1) antibody levels in Japanese children [J].

Quan, Liangliang ;

Morita, Reiji ;

Kawakami, Shigehiko .

BURNS, 2010, 36 (05) :716-721

[10]

Smit MA, 2013, EMERG INFECT DIS, V19, P1855, DOI [10.3201/eid1911.121547, 10.3201/eid1011.121547]

← 1 2 →