Fast high-resolution protein structure determination by using unassigned NMR data

被引：11

作者：

Korukottu, Jegannath ^{[1
]}

Bayrhuber, Monika ^{[1
]}

Montaville, Pierre ^{[1
]}

Vijayan, Vinesh ^{[1
]}

Jung, Young-Sang ^{[1
]}

Becker, Stefan ^{[1
]}

Zweckstetter, Markus ^{[1
]}

机构：

[1] Max Planck Inst Biophys Chem, Dept NMR Based Struct Biol, D-37077 Gottingen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 07期

关键词：

genomics; NMR spectroscopy; protein structures; structure elucidation;

D O I：

10.1002/anie.200603213

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) The major bottleneck of rapid NMR-based structure determination is data analysis. The solution to this problem is a method that enables automatic high-resolution protein-structure determination from unassigned, experimental NMR data without manual intervention in less than 24 h. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1176 / 1179

页数：4

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