The cut-off value of 100 mg/dl is insufficient to detect heterozygous α-1 antitrypsin-deficient liver disease patients

被引：8
作者：
Kok, Karin F. [1 ]
Willems, Hans L. [2 ]
Drenth, Joost P. H. [1 ]
机构：
[1] Radboud Univ Nijmegen, Med Ctr, Dept Gastroenterol & Hepatol, NL-6525 ED Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Med Ctr, Dept Lab Med, NL-6525 ED Nijmegen, Netherlands
来源：
LIVER INTERNATIONAL | 2010年 / 30卷 / 03期
关键词：
ALPHA(1)-ANTITRYPSIN DEFICIENCY; ALPHA-1-ANTITRYPSIN DEFICIENCY; DIAGNOSIS;
D O I：
10.1111/j.1478-3231.2009.02179.x
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
[No abstract available]
引用
收藏
页码：491 / 492
页数：2
相关论文
共 9 条
[1]   Enhanced phenotypic expression of alpha-1-antitrypsin deficiency in an MZ heterozygote with chronic hepatitis C [J].
Banner, BF ;
Karamitsios, N ;
Smith, L ;
Bonkovsky, HL .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 1998, 93 (09) :1541-1545
[2]   Laboratory diagnosis of alpha1-antitrypsin deficiency [J].
Ferrarotti, Ilaria ;
Scabini, Roberta ;
Campo, Ilaria ;
Ottaviani, Stefania ;
Zorzetto, Michele ;
Gorrini, Marina ;
Luisetti, Maurizio .
TRANSLATIONAL RESEARCH, 2007, 150 (05) :267-274
[3]   α1-Antitrypsin deficiency: best clinical practice [J].
Kalsheker, N. A. .
JOURNAL OF CLINICAL PATHOLOGY, 2009, 62 (10) :865-869
[4]   THE MECHANISM OF Z-ALPHA-1-ANTITRYPSIN ACCUMULATION IN THE LIVER [J].
LOMAS, DA ;
EVANS, DL ;
FINCH, JT ;
CARRELL, RW .
NATURE, 1992, 357 (6379) :605-607
[5]   Diagnosis of α-1-antitrypsin deficiency:: An algorithm of quantification, genotyping, and phenotyping [J].
Snyder, Melissa R. ;
Katzmann, Jerry A. ;
Butz, Malinda L. ;
Yang, Ping ;
Dawson, D. Brian ;
Halling, Kevin C. ;
Highsmith, W. Edward ;
Thibodeau, Stephen N. .
CLINICAL CHEMISTRY, 2006, 52 (12) :2236-2242
[6]   Myths and Misconceptions About α1-Antitrypsin Deficiency [J].
Stoller, James K. ;
Aboussouan, Loutfi S. .
ARCHIVES OF INTERNAL MEDICINE, 2009, 169 (06) :546-550
[7]   α1-antitrypsin deficiency [J].
Stoller, JK ;
Aboussouan, LS .
LANCET, 2005, 365 (9478) :2225-2236
[8]   Transplantation for end stage liver disease related to alpha 1 antitrypsin [J].
Vennarecci, G ;
Gunson, BK ;
Ismail, T ;
Hubscher, SG ;
Kelly, DA ;
McMaster, P ;
Elias, E .
TRANSPLANTATION, 1996, 61 (10) :1488-1495
[9]   SERPINA1 gene variants in individuals from the general population with reduced α1-antitrypsin concentrations [J].
Zorzetto, Michele ;
Russi, Erich ;
Senn, Oliver ;
Imboden, Medea ;
Ferrarotti, Ilaria ;
Tinelli, Carmine ;
Campo, Ilaria ;
Ottaviani, Stefania ;
Scabini, Roberta ;
von Eckardstein, Arnold ;
Berger, Wolfgang ;
Braendli, Otto ;
Rochat, Thierry ;
Luisetti, Maurizio ;
Probst-Hensch, Nicole .
CLINICAL CHEMISTRY, 2008, 54 (08) :1331-1338
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