Microwave promoted efficient synthesis of substituted uracils and thiouracils under solvent-free conditions

被引：36

作者：

Mojtahedi, MM

Saidi, MR ^{[1
]}

Shirzi, JS

Bolourtchian, M

机构：

[1] Sharif Univ Technol, Dept Chem, Tehran, Iran

[2] Chem & Chem Engn Res Ctr Iran, Tehran, Iran

来源：

SYNTHETIC COMMUNICATIONS | 2002年 / 32卷 / 06期

关键词：

D O I：

10.1081/SCC-120002693

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several substituted uracils and thiouracils were synthesized in good yields by one-pot condensation reaction of methyl or ethyl beta-ketoesters and urea (or thiourea) in solvent-free conditions under microwave irradiation and in short time.

引用

页码：851 / 855

页数：5

共 20 条

[1]

ABRAMOVITCH RA, 1991, ORG PREP PROCED INT, V23, P685

[2] STUDIES IN CHEMOTHERAPY .10. ANTITHYROID COMPOUNDS - SYNTHESIS OF 5-SUBSTITUTED AND 6-SUBSTITUTED 2-THIOURACILS FROM BETA-OXOESTERS AND THIOUREA [J].

ANDERSON, GW ;

HALVERSTADT, IF ;

MILLER, WH ;

ROBLIN, RO .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1945, 67 (12) :2197-2200

[3]

BUCKINGHAM J, 1992, DICT ORGANIC COMPOUN

[4]

Cassidy S B, 1984, Curr Probl Pediatr, V14, P1

[5]

LAMON RW, 1986, J HETEROCYCLIC CHEM, V5, P837

[6]

LAPUCHA AR, 1987, SYNTHESIS-STUTTGART, P256

[7]

MAJETICH G, 1995, J MICROWAVE POWER EE, V30, P27

[8] APPLICATIONS OF MICROWAVE DIELECTRIC HEATING EFFECTS TO SYNTHETIC PROBLEMS IN CHEMISTRY [J].

MINGOS, DMP ;

BAGHURST, DR .

CHEMICAL SOCIETY REVIEWS, 1991, 20 (01) :1-47

[9] A novel method for the synthesis of disubstituted ureas and thioureas under microwave irradiaton [J].

Mojtahedi, MM ;

Saidi, MR ;

Bolourtchian, M .

JOURNAL OF CHEMICAL RESEARCH-S, 1999, (12) :710-711

[10] Microwave-assisted aminomethylation of electron-rich compounds under solvent-free condition [J].

Mojtahedi, MM ;

Sharifi, A ;

Mohsenzadeh, F ;

Saidi, MR .

SYNTHETIC COMMUNICATIONS, 2000, 30 (01) :69-72

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