Progressive severe B cell and NK cell deficiency with T cell senescence in adult CD40L deficiency

被引：5

作者：

Lougaris, Vassilios ^{[1
,2
]}

Lanzi, Gaetana ^{[3
]}

Baronio, Manuela ^{[1
,2
]}

Gazzurelli, Luisa ^{[1
,2
]}

Vairo, Donatella ^{[3
]}

Lorenzini, Tiziana ^{[1
,2
]}

Badolato, Raffaele ^{[1
,2
]}

Notarangelo, Lucia Dora ^{[4
]}

Boschi, Andrea ^{[5
]}

Moratto, Daniele ^{[3
]}

Plebani, Alessandro ^{[1
,2
]}

机构：

[1] Univ Brescia, ASST Spedali Civili Brescia, Pediat Clin, Piazzale Spedali Civili 1, I-25123 Brescia, Italy

[2] Univ Brescia, ASST Spedali Civili Brescia, Dept Clin & Expt Sci, Inst Mol Med A Nocivelli, Piazzale Spedali Civili 1, I-25123 Brescia, Italy

[3] Univ Brescia, ASST Spedali Civili Brescia, Inst Mol Med A Nocivelli,Dept Mol & Translat Med, Dept Pathol,Lab Genet Disorders Childhood, Brescia, Italy

[4] ASST Spedali Civili Brescia, Pediat Oncohematol, Brescia, Italy

[5] Rimini Hosp, Infect Dis Unit, Rimini, Italy

来源：

CLINICAL IMMUNOLOGY | 2018年 / 190卷

关键词：

CD40 ligand deficiency; B cells; Natural killer (NK) cells; CD4 T cells; T cell senescence; HYPER-IGM SYNDROME; DEFECTIVE EXPRESSION; LIGAND DEFICIENCY; IMMUNODEFICIENCY;

D O I：

10.1016/j.clim.2018.02.008

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：11 / 14

页数：4

共 13 条

[1] CD40 LIGAND GENE DEFECTS RESPONSIBLE FOR X-LINKED HYPER-IGM SYNDROME [J].

ALLEN, RC ;

ARMITAGE, RJ ;

CONLEY, ME ;

ROSENBLATT, H ;

JENKINS, NA ;

COPELAND, NG ;

BEDELL, MA ;

EDELHOFF, S ;

DISTECHE, CM ;

SIMONEAUX, DK ;

FANSLOW, WC ;

BELMONT, J ;

SPRIGGS, MK .

SCIENCE, 1993, 259 (5097) :990-993

[2] THE CD40 LIGAND, GP39, IS DEFECTIVE IN ACTIVATED T-CELLS FROM PATIENTS WITH X-LINKED HYPER-IGM SYNDROME [J].

ARUFFO, A ;

FARRINGTON, M ;

HOLLENBAUGH, D ;

LI, X ;

MILATOVICH, A ;

NONOYAMA, S ;

BAJORATH, J ;

GROSMAIRE, LS ;

STENKAMP, R ;

NEUBAUER, M ;

ROBERTS, RL ;

NOELLE, RJ ;

LEDBETTER, JA ;

FRANCKE, U ;

OCHS, HD .

CELL, 1993, 72 (02) :291-300

[3] Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells [J].

Brenchley, JM ;

Karandikar, NJ ;

Betts, MR ;

Ambrozak, DR ;

Hill, BJ ;

Crotty, LE ;

Casazza, JP ;

Kuruppu, J ;

Migueles, SA ;

Connors, M ;

Roederer, M ;

Douek, DC ;

Koup, RA .

BLOOD, 2003, 101 (07) :2711-2720

[4] A new mechanism of NK cell cytotoxicity activation: The CD40-CD40 ligand interaction [J].

Carbone, E ;

Ruggiero, G ;

Terrazzano, G ;

Palomba, C ;

Manzo, C ;

Fontana, S ;

Spits, H ;

Karre, K ;

Zappacosta, S .

JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 185 (12) :2053-2060

[5] Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation [J].

de la Morena, M. Teresa ;

Leonard, David ;

Torgerson, Troy R. ;

Cabral-Marques, Otavio ;

Slatter, Mary ;

Aghamohammadi, Asghar ;

Chandra, Sharat ;

Murguia-Favela, Luis ;

Bonilla, Francisco A. ;

Kanariou, Maria ;

Damrongwatanasuk, Rongras ;

Kuo, Caroline Y. ;

Dvorak, Christopher C. ;

Meyts, Isabelle ;

Chen, Karin ;

Kobrynski, Lisa ;

Kapoor, Neena ;

Richter, Darko ;

DiGiovanni, Daniela ;

Dhalla, Fatima ;

Farmaki, Evangelia ;

Speckmann, Carsten ;

Espanol, Teresa ;

Shcherbina, Anna ;

Hanson, Imelda Celine ;

Litzman, Jiri ;

Routes, John M. ;

Wong, Melanie ;

Fuleihan, Ramsay ;

Seneviratne, Suranjith L. ;

Small, Trudy N. ;

Janda, Ales ;

Bezrodnik, Liliana ;

Seger, Reinhard ;

Raccio, Andrea Gomez ;

Edgar, J. David M. ;

Chou, Janet ;

Abbott, Jordan K. ;

van Montfrans, Joris ;

Gonzalez-Granado, Luis Ignacio ;

Bunin, Nancy ;

Kutukculer, Necil ;

Gray, Paul ;

Seminario, Gisela ;

Pasic, Srdjan ;

Aquino, Victor ;

Wysocki, Christian ;

Abolhassani, Hassan ;

Dorsey, Morna ;

Cunningham-Rundles, Charlotte .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2017, 139 (04) :1282-1292

[6] Cross-talk between CD40 and CD40L: lessons from primary immune deficiencies [J].

Ferrari, Simona ;

Plebani, Alessandro .

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, 2002, 2 (06) :489-494

[7] CD40L expression permits CD8+ T cells to execute immunologic helper functions [J].

Frentsch, Marco ;

Stark, Regina ;

Matzmohr, Nadine ;

Meier, Sarah ;

Durlanik, Sibel ;

Schulz, Axel R. ;

Stervbo, Ulrik ;

Juerchott, Karsten ;

Gebhardt, Friedemann ;

Heine, Guido ;

Reuter, Morgan A. ;

Betts, Michael R. ;

Busch, Dirk ;

Thiel, Andreas .

BLOOD, 2013, 122 (03) :405-412

[8] DEFECTIVE EXPRESSION OF THE CD40 LIGAND IN X-CHROMOSOME-LINKED IMMUNOGLOBULIN DEFICIENCY WITH NORMAL OR ELEVATED IGM [J].

FULEIHAN, R ;

RAMESH, N ;

LOH, R ;

JABARA, H ;

ROSEN, FS ;

CHATILA, T ;

FU, SM ;

STAMENKOVIC, I ;

GEHA, RS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (06) :2170-2173

[9]

Katz F, 1996, HUM MUTAT, V8, P223, DOI 10.1002/(SICI)1098-1004(1996)8:3<223::AID-HUMU5>3.0.CO

[10]

2-A

← 1 2 →