Radiotherapy After Mastectomy

被引：3
作者：
Blitzblau, Rachel C. [1 ]
Horton, Janet K. [1 ]
机构：
[1] Duke Univ, Med Ctr, Dept Radiat Oncol, Durham, NC 27710 USA
来源：
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2013年 / 22卷 / 03期
关键词：
Breast cancer; Mastectomy; Radiotherapy; Biologic subtype; BREAST-CANCER PATIENTS; SURGICAL ADJUVANT BREAST; POSITIVE AXILLARY NODES; PATHOLOGICAL COMPLETE RESPONSE; DOXORUBICIN-BASED CHEMOTHERAPY; LOCOREGIONAL RECURRENCE RISK; LOCAL-REGIONAL RECURRENCE; TUMORS; CM; NEOADJUVANT CHEMOTHERAPY; ESTROGEN-RECEPTOR;
D O I：
10.1016/j.soc.2013.02.012
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Classic randomized trials documented the benefit of postmastectomy radiotherapy in women with node-positive or locally advanced breast cancer. Modern advances in surgical therapy, systemic therapy, and radiotherapy, however, along with an improved understanding of cancer biology, have called into question previously assumed recurrence risks and treatment benefits. This article explores the impact of tumor biology and genomic medicine on utilization of postmastectomy radiotherapy and how treatment decision-making is moving beyond TNM-based predictors.
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页码：563 / +
页数：16
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