Research Advances in the Correlation between Peroxisome Proliferator-Activated Receptor-γ and Digestive Cancers

被引：8
|
作者：
Xu, Shuqi [1 ]
Xu, Xuanfu [1 ]
机构：
[1] Anhui Med Univ, Shidong Hosp Shanghai, Dept Gastroenterol, Shanghai 200433, Peoples R China
来源：
PPAR RESEARCH | 2018年 / 2018卷
关键词：
PPAR-GAMMA; COLORECTAL-CANCER; PANCREATIC-CANCER; GENE-EXPRESSION; CELLS; AGONIST; ALPHA; MACROPHAGES; COMBINATION; METASTASIS;
D O I：
10.1155/2018/5289859
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Peroxisome proliferator-activated receptor-gamma (PPAR gamma) is a class of ligand-activated nuclear transcription factors, which is a member of type II nuclear receptor superfamily. Previous studies demonstrate that PPAR gamma is expressed in a variety of tumor tissues and is closely associated with the proliferation and prognosis of digestive system tumors by its roles in mediation of cell differentiation, induction of cell apoptosis, and inhibition of cell proliferation.
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页数：7
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