Photoactivatable HNO-releasing compounds using the retro-Diels-Alder reaction

被引：41

作者：

Adachi, Yusuke ^{[1
]}

Nakagawa, Hidehiko ^{[1
]}

Matsuo, Kazuya ^{[1
]}

Suzuki, Takayoshi ^{[1
]}

Miyata, Naoki ^{[1
]}

机构：

[1] Nagoya City Univ, Grad Sch Pharmaceut Sci, Mizuho Ku, Aichi 4678673, Japan

来源：

CHEMICAL COMMUNICATIONS | 2008年 / 41期

关键词：

D O I：

10.1039/b811985f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We synthesized hetero-Diels-Alder cycloadducts from acyl nitroso derivatives and 9,10-dimethylanthracene, to be photo-inducible HNO-releasing agents and found that introduction of conjugated nitroaromatic groups effectively enhanced the responsiveness of HNO release to UV-A irradiation; we confirmed photoinduced HNO formation by EPR and GCMS analysis.

引用

页码：5149 / 5151

页数：3

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