Risk factors for prosthetic joint infection: Case-control study

被引:561
作者
Berbari, EF
Hanssen, AD
Duffy, MC
Steckelberg, JM
Ilstrup, DM
Harmsen, WS
Osmon, DR
机构
[1] Mayo Clin & Mayo Fdn, Dept Internal Med, Div Infect Dis, Rochester, MN 55905 USA
[2] Mayo Clin & Mayo Fdn, Dept Orthoped, Rochester, MN 55905 USA
[3] Mayo Clin & Mayo Fdn, Biostat Sect, Rochester, MN 55905 USA
关键词
D O I
10.1086/514991
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We conducted a matched case-control study tea determine risk factors for the development of prosthetic joint infection. Cases were patients with prosthetic hip or knee joint infection. Controls were patients who underwent total hip or knee arthroplasty and did not develop prosthetic joint infection. A multiple logistic regression model indicated that risk factors for prosthetic joint infection were the development of a surgical site infection not involving the prosthesis (odds ratio [OR], 35.9; 95% confidence interval [CI], 8.3-154.6), a National Nosocomial Infections Surveillance (NNIS) System surgical patient risk index score of 1 (OR, 1.7; 95% CI, 1.2-2.3) or 2 (OR, 3.9; 95% CI, 2.0-7.5), the presence of a malignancy (OR, 3.1; 95% CI, 1.3-7.2)., and a history of joint arthroplasty (OR, 2.0; 95% CI, 1.4-3.0). Our findings suggest that a surgical site infection not involving the joint prosthesis, an NNIS System surgical patient risk index score of 1 or 2, the presence of a malignancy, and a history of a joint arthroplasty are associated with an increased risk of prosthetic joint infection.
引用
收藏
页码:1247 / 1254
页数:8
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