Dynamic contrast-enhanced magnetic resonance imaging: definitive imaging of placental function?

被引：26

作者：

Chalouhi, G. E. ^{[2
,3
]}

Deloison, B. ^{[2
,3
]}

Siauve, N. ^{[2
,3
,4
]}

Aimot, S. ^{[2
,3
]}

Balvay, D. ^{[2
,3
]}

Cuenod, C. A. ^{[2
,3
,4
]}

Ville, Y.

Clement, O. ^{[2
,3
]}

Salomon, L. J. ^{[1
,2
,3
]}

机构：

[1] Univ Paris 05, Hop Necker Enfants Malades, AP HP, Dept Obstet & Gynecol,Serv Gynecol Obstet, F-75015 Paris, France

[2] INSERM, Paris Cardiovasc Res Ctr PARCC, LRI, U970,Equipe 2, F-75015 Paris, France

[3] Univ Paris 05, UMR S970, F-75015 Paris, France

[4] Hop Europeen Georges Pompidou, AP HP, Dept Radiol, F-75015 Paris, France

来源：

SEMINARS IN FETAL & NEONATAL MEDICINE | 2011年 / 16卷 / 01期

关键词：

Blood oxygen level-dependent (BOLD) effect; Dynamic contrast-enhanced magnetic resonance imaging (DCE MRI); Functional magnetic resonance imaging (fMRI); Perfusion; Placenta; BOLD CONTRAST; IN-UTERO; OXYGENATION; FETAL; PERFUSION; ULTRASOUND; PREGNANCY; HYPOXIA; MRI; PREECLAMPSIA;

D O I：

10.1016/j.siny.2010.09.001

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The placenta constitutes a complex circulatory interface between the mother and fetus, but the relationship between the maternal and fetal circulation is still very difficult to study in vivo. There is growing evidence that magnetic resonance imaging (MRI) is useful and safe during pregnancy, and MRI is increasingly used for fetal and placental anatomical imaging. MRI functional imaging is now a modern obstetric tool and has the potential to provide new insights into the physiology of the human placenta. Placental perfusion has been studied during the first pass of an MR contrast agent, by arterial spin labeling, diffusion imaging, T1 and T2 relaxation time measurement using echo-planar imaging, and by a combination of magnetization transfer with established stereological methods. The BOLD (blood oxygen level-dependent) effect offers new perspectives for functional MRI evaluation of the placenta. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：22 / 28

页数：7

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