Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure

被引：0

作者：

Muns, Sofia M. ^{[1
]}

Gonzalez, Monica P. ^{[1
]}

Villegas, Victor M. ^{[1
,2
,3
]}

de la Vega, Gabriela ^{[4
]}

Ventura, Camila V. ^{[5
,6
]}

Berrocal, Audina M. ^{[2
]}

机构：

[1] Univ Puerto Rico, Dept Ophthalmol, Med Sci Campus, San Juan, PR 00936 USA

[2] Univ Miami, Miller Sch Med, Bascom Palmer Eye Inst, Miami, FL 33136 USA

[3] Ponce Hlth Sci Univ, Dept Surg, Ponce, PR 00732 USA

[4] HIMA San Pablo Hosp, Dept Radiol, Caguas, PR 00726 USA

[5] Altino Ventura Fdn, Dept Ophthalmol, Recife, PE, Brazil

[6] HOPE Eye Hosp, Dept Ophthalmol, Recife, PE, Brazil

来源：

INTERNATIONAL JOURNAL OF RETINA AND VITREOUS | 2020年 / 6卷 / 01期

关键词：

Zika virus; Morning glory disc anomaly; Optic disc; Excavated disc anomaly; Coloboma; OPHTHALMIC MANIFESTATIONS; INFANTS;

D O I：

10.1186/s40942-020-00240-1

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

BackgroundTo report a case of morning glory disc anomaly (MGDA) in a pediatric patient with prenatal Zika virus (ZIKV) exposure.Case presentationA 3-year-old male with prenatal exposure to ZIKV, confirmed by real-time polymerase chain reaction testing during the second trimester of pregnancy, was evaluated due to visual loss. Physical examination was remarkable for unilateral MGDA. Neuroimaging showed a base of skull encephalocele through the floor of the sella and callosal dysgenesis.ConclusionsThis is the first report to suggest an association between prenatal ZIKV exposure and MGDA. Prenatal ZIKV exposure may be associated to a wider pathologic spectrum than previously reported.

引用

页数：5

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