Biocompatibility and drug delivery systems

被引：214
作者：
Kohane, Daniel S. [1 ]
Langer, Robert [2 ]
机构：
[1] Harvard Univ, Sch Med, Lab Biomat & Drug Delivery, Dept Anesthesiol,Div Crit Care Med,Childrens Hosp, Boston, MA 02115 USA
[2] MIT, Koch Inst Integrat Canc Technol, Cambridge, MA 02139 USA
来源：
CHEMICAL SCIENCE | 2010年 / 1卷 / 04期
关键词：
DURATION LOCAL-ANESTHESIA; PROTEIN-SUGAR PARTICLES; SCIATIC-NERVE BLOCKADE; HYALURONIC-ACID; IN-VIVO; POSTSURGICAL ADHESIONS; PLASMINOGEN-ACTIVATOR; RABBIT MODEL; BUPIVACAINE; BIOMATERIALS;
D O I：
10.1039/c0sc00203h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Drug delivery technology has emerged as an important focus of biotechnological research and commercial enterprise. While much attention is justifiably focused on the design and effectiveness of drug delivery devices, the nature of their interaction with surrounding tissues their biocompatibility is crucial. Here we discuss biocompatibility, specifically as it relates to drug delivery systems, which differ from other biomaterial-based devices by possibly containing large quantities of drugs with their own effects on tissues.
引用
收藏
页码：441 / 446
页数：6
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