Clean synthesis of 1,8-dioxooctahydroxanthenes promoted by DABCO-bromine in aqueous media

被引：34
作者：
Bigdeli, Mohammadali [1 ]
机构：
[1] Tarbiat Moallem Univ, Fac Chem, Tehran, Iran
来源：
CHINESE CHEMICAL LETTERS | 2010年 / 21卷 / 10期
关键词：
1,4-Diazabicyclo[2,2,2]octane; (DABCO)-bromine; Octahydroxyxanthene; Aqueous media; Arylaldehyde; Dimedone; DERIVATIVES; EFFICIENT; CYCLIZATION; XANTHENES; COMPLEX; ACID;
D O I：
10.1016/j.cclet.2010.05.018
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient procedure is reported for the synthesis of 3,3,6,6-tetramethyl-9-aryl-1,8-dioxooctahydroxanthenes using a one-pot condensation of arylaldehydes and 5,5-dimethyl-1,3-cyclohexandione in the presence of DABCO-bromine (TDB) as an acid catalyst. To the best of our knowledge this is the first time that DABCO-bromine is used as an acid catalyst in aqueous media for this type of reaction. This method provides several advantages such as use of water as solvent, easy and clean synthesis, simple work up and versatility. (C) 2010 Mohammadali Bigdeli. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码：1180 / 1182
页数：3
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