The forgotten class of drugs for multiple myeloma: HDAC inhibitors

被引:6
作者
Biran, Noa
Siegel, David S. [1 ]
Vesole, David H.
机构
[1] Hackensack Univ Med Ctr, John Theurer Canc Ctr, Hackensack, NJ 07601 USA
关键词
BORTEZOMIB; DEXAMETHASONE; COMBINATION; LENALIDOMIDE; VORINOSTAT;
D O I
10.1016/S2352-3026(18)30194-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E604 / E605
页数:2
相关论文
共 10 条
[1]  
Andrzej J, 2017, P AM SOC CLIN ONCO S, V35, P8000
[2]   Vorinostat or placebo in combination with bortezomib in patients with multiple myeloma (VANTAGE 088): a multicentre, randomised, double-blind study [J].
Dimopoulos, Meletios ;
Siegel, David S. ;
Lonial, Sagar ;
Qi, Junyuan ;
Hajek, Roman ;
Facon, Thierry ;
Rosinol, Laura ;
Williams, Catherine ;
Blacklock, Hilary ;
Goldschmidt, Hartmut ;
Hungria, Vania ;
Spencer, Andrew ;
Palumbo, Antonio ;
Graef, Thorsten ;
Eid, Joseph E. ;
Houp, Jennifer ;
Sun, Linda ;
Vuocolo, Scott ;
Anderson, Kenneth C. .
LANCET ONCOLOGY, 2013, 14 (11) :1129-1140
[3]   Bortezomib with lenalidomide and dexamethasone versus lenalidomide and dexamethasone alone in patients with newly diagnosed myeloma without intent for immediate autologous stem-cell transplant (SWOG S0777): a randomised, open-label, phase 3 trial [J].
Durie, Brian G. M. ;
Hoering, Antje ;
Abidi, Muneer H. ;
Rajkumar, S. Vincent ;
Epstein, Joshua ;
Kahanic, Stephen P. ;
Thakuri, Mohan ;
Reu, Frederic ;
Reynolds, Christopher M. ;
Sexton, Rachael ;
Orlowski, Robert Z. ;
Barlogie, Bart ;
Dispenzieri, Angela .
LANCET, 2017, 389 (10068) :519-527
[4]   A phase 1/2 study of carfilzomib in combination with lenalidomide and low-dose dexamethasone as a frontline treatment for multiple myeloma [J].
Jakubowiak, Andrzej J. ;
Dytfeld, Dominik ;
Griffith, Kent A. ;
Lebovic, Daniel ;
Vesole, David H. ;
Jagannath, Sundar ;
Al-Zoubi, Ammar ;
Anderson, Tara ;
Nordgren, Brian ;
Detweiler-Short, Kristen ;
Stockerl-Goldstein, Keith ;
Ahmed, Asra ;
Jobkar, Terri ;
Durecki, Diane E. ;
McDonnell, Kathryn ;
Mietzel, Melissa ;
Couriel, Daniel ;
Kaminski, Mark ;
Vij, Ravi .
BLOOD, 2012, 120 (09) :1801-1809
[5]  
Kaufman JL, 2012, ASH ANN M, V120, P336
[6]   Bortezomib, lenalidomide, and dexamethasone with panobinostat for front-line treatment of patients with multiple myeloma who are eligible for transplantation: a phase 1 trial [J].
Manasanch, Elisabet E. ;
Shah, Jatin J. ;
Lee, Hans C. ;
Weber, Donna M. ;
Thomas, Sheeba K. ;
Amini, Behrang ;
Feng, Lei ;
Berkova, Zuzana ;
Hildebrandt, Michelle ;
Orlowski, Robert Z. .
LANCET HAEMATOLOGY, 2018, 5 (12) :E628-E640
[7]   Daratumumab plus Bortezomib, Melphalan, and Prednisone for Untreated Myeloma [J].
Mateos, M. -V. ;
Dimopoulos, M. A. ;
Cavo, M. ;
Suzuki, K. ;
Jakubowiak, A. ;
Knop, S. ;
Doyen, C. ;
Lucio, P. ;
Nagy, Z. ;
Kaplan, P. ;
Pour, L. ;
Cook, M. ;
Grosicki, S. ;
Crepaldi, A. ;
Liberati, A. M. ;
Campbell, P. ;
Shelekhova, T. ;
Yoon, S. -S. ;
Iosava, G. ;
Fujisaki, T. ;
Garg, M. ;
Chiu, C. ;
Wang, J. ;
Carson, R. ;
Crist, W. ;
Deraedt, W. ;
Nguyen, H. ;
Qi, M. ;
San-Miguel, J. .
NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (06) :518-528
[8]   Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications [J].
Mitsiades, CS ;
Mitsiades, NS ;
McMullan, CJ ;
Poulaki, V ;
Shringarpure, R ;
Hideshima, T ;
Akiyama, M ;
Chauhan, D ;
Munshi, N ;
Gu, XS ;
Bailey, C ;
Joseph, M ;
Libermann, TA ;
Richon, VM ;
Marks, PA ;
Anderson, KC .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (02) :540-545
[9]   A phase IIb trial of vorinostat in combination with lenalidomide and dexamethasone in patients with multiple myeloma refractory to previous lenalidomide-containing regimens [J].
Sanchez, Larysa ;
Vesole, David H. ;
Richter, Joshua R. ;
Biran, Noa ;
Bilotti, Elizabeth ;
McBride, Laura ;
Anand, Palka ;
Ivanovski, Kristin ;
Siegel, David S. .
BRITISH JOURNAL OF HAEMATOLOGY, 2017, 176 (03) :440-447
[10]   Ricolinostat, the First Selective Histone Deacetylase 6 Inhibitor, in Combination with Bortezomib and Dexamethasone for Relapsed or Refractory Multiple Myeloma [J].
Vogl, Dan T. ;
Raje, Noopur ;
Jagannath, Sundar ;
Richardson, Paul ;
Hari, Parameswaran ;
Orlowski, Robert ;
Supko, Jeffrey G. ;
Tamang, David ;
Yang, Min ;
Jones, Simon S. ;
Wheeler, Catherine ;
Markelewicz, Robert J. ;
Lonial, Sagar .
CLINICAL CANCER RESEARCH, 2017, 23 (13) :3307-3315