Diffusion-weighted MRI in prostate cancer - comparison between single-shot fast spin echo and echo planar imaging sequences

被引:36
作者
Kozlowski, Piotr [1 ,2 ,3 ]
Chang, Silvia D. [1 ,3 ]
Goldenberg, S. Larry [1 ,2 ]
机构
[1] Vancouver Gen Hosp, Prostate Ctr, Vancouver, BC V6H 3Z6, Canada
[2] Univ British Columbia, Dept Urol Sci, Vancouver, BC V5Z 1M9, Canada
[3] Univ British Columbia, Dept Radiol, Vancouver, BC V5Z 4E3, Canada
关键词
diffusion MRI; prostate cancer; fast spin echo; echo planar imaging;
D O I
10.1016/j.mri.2007.04.008
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Diffusion-weighted (DW) MRI at 1.5 T was carried out in two groups of patients. MRI data were correlated with the biopsy and histopathology (where available). The performance of two sequences-a single-shot FSE (14 patients) and a single-shot EPI (15 patients) was compared. Average ADC values from the normal peripheral zone (PZ), central gland (CG) and the tumour [prostate carcinoma (PCa)] were calculated from b values of 0 and 600. Tukey-Kramer test was used for statistical analysis. EPI produced higher values of ADC (10(-3) mm(2)/s) than FSE sequence: 1.992 +/- 0.208 vs. 1.573 +/- 0.270 in PZ (P <.001), 1.518 +/- 0.126 vs. 1.373 +/- 0.179 in CG and 1.214 +/- 0.254 vs. 0.993 +/- 0.158 in PCa (P <.01). In conclusion, both EPI and FSE sequences showed differences in ADC between normal PZ, CG and PCa; however, EPI produced significantly higher ADC values than FSE. Crown Copyright (c) 2008 Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:72 / 76
页数:5
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