Pathophysiology and treatment of IgA nephropathy in children

被引：74
作者：
Yoshikawa, N
Tanaka, R
Iijima, K
机构：
[1] Wakayama Med Univ, Dept Pediat, Wakayama 6418510, Japan
[2] Kobe Univ, Sch Med, Dept Pediat, Kobe, Hyogo 650, Japan
来源：
PEDIATRIC NEPHROLOGY | 2001年 / 16卷 / 05期
关键词：
pathogenesis; treatment; IgA nephropathy; genetic factors;
D O I：
10.1007/s004670100582
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
IgA nephropathy is the most-common primary glomerulonephritis worldwide, and about 20%-50% of patients develop progressive renal failure. The pathogenesis is still unknown and treatment has not yet been established. Knowledge concerning childhood IgA nephropathy has expanded greatly in the last 10 years, and its importance as the major form of glomerulonephritis and major contributor to end-stage renal disease is also becoming apparent in children. This review focuses on the pathophysiology and treatment of IgA nephropathy in children.
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页码：446 / 457
页数：12
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