Smart Nanomaterials Employed Recently for Drug Delivery in Cancer Therapy: an Intelligent Approach

被引:8
作者
Chauhan, Nidhi [1 ]
Saxena, Kirti [1 ]
Jain, Utkarsh [1 ]
机构
[1] Amity Univ Uttar Pradesh AUUP, Amity Inst Nanotechnol AINT, Sect 125, Noida 201313, India
关键词
Drug delivery; Cancer; Smart nanomaterials; Nanocarriers; MESOPOROUS SILICA NANOPARTICLES; NANO-CARRIERS;
D O I
10.1007/s12668-022-01022-9
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Smart nanomaterials are extensively studied for their significance as a nanocarrier towards cancer treatment. Nanomaterial-based drug delivery systems provide improved biocompatibility and stability, precise targeting, enhanced permeability, and controlled release of drugs even in the harsh tumor microenvironment. The recently used smart and advanced nanomaterials, such as mesoporous silica, metal oxides, black phosphorous, polymers, and organic framework, are highlighted in this article. A general approach of drug delivery in cancer cells is also discussed. The incorporation of nanocomposite, nanohybrid as drug delivery system, has led chemotherapy to the next level.
引用
收藏
页码:1356 / 1365
页数:10
相关论文
共 41 条
[2]   pH-Sensitive Dendrimersomes of Hybrid Triazine-Carbosilane Dendritic Amphiphiles-Smart Vehicles for Drug Delivery [J].
Apartsin, Evgeny ;
Knauer, Nadezhda ;
Arkhipova, Valeria ;
Pashkina, Ekaterina ;
Aktanova, Alina ;
Poletaeva, Julia ;
Sanchez-Nieves, Javier ;
de la Mata, Francisco Javier ;
Gomez, Rafael .
NANOMATERIALS, 2020, 10 (10) :1-15
[3]   Sericin/RBA embedded gellan gum based smart nanosystem for pH responsive drug delivery [J].
Arjama, Mukherjee ;
Mehnath, Sivaraj ;
Rajan, Mariappan ;
Jeyaraj, Murugaraj .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 120 :1561-1571
[4]   Chlorin e6 decorated doxorubicin encapsulated chitosan nanoparticles for photo-controlled cancer drug delivery [J].
Bhatta, Anindita ;
Krishnamoorthy, Ganesan ;
Marimuthu, Nidhin ;
Dihingia, Anjum ;
Manna, Prasenjit ;
Biswal, Himadree Tanaya ;
Das, Minati ;
Krishnamoorthy, Govindarajan .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 136 :951-961
[5]   Cathepsin B-responsive and gadolinium-labeled branched glycopolymer-PTX conjugate-derived nanotheranostics for cancer treatment [J].
Cai, Hao ;
Xiang, Yufan ;
Zeng, Yujun ;
Li, Zhiqian ;
Zheng, Xiuli ;
Luo, Qiang ;
Zhu, Hongyan ;
Gong, Qiyong ;
Gu, Zhongwei ;
Liu, Yanhui ;
Zhang, Hu ;
Luo, Kui .
ACTA PHARMACEUTICA SINICA B, 2021, 11 (02) :544-559
[6]   A self-targeting and controllable drug delivery system constituting mesoporous silica nanoparticles fabricated with a multi-stimuli responsive chitosan-based thin film layer [J].
Chen, Chao ;
Yao, Wenji ;
Sun, Wen ;
Guo, Tianyuan ;
Lv, Hangya ;
Wang, Xiaoli ;
Ying, Hanjie ;
Wang, Yibing ;
Wang, Ping .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 122 :1090-1099
[7]   Continuous flow fabrication of Fmoc-cysteine based nanobowl infused core-shell like microstructures for pH switchable on-demand anti-cancer drug delivery [J].
Chibh, Sonika ;
Katoch, Vibhav ;
Kour, Avneet ;
Khanam, Farheen ;
Yadav, Amit Singh ;
Singh, Manish ;
Kundu, Gopal C. ;
Prakash, Bhanu ;
Panda, Jiban Jyoti .
BIOMATERIALS SCIENCE, 2021, 9 (03) :942-959
[8]  
Chu E., 2004, BASIC CLIN PHARMACOL, V9th, P898
[9]   Cathepsin-sensitive nanoscale drug delivery systems for cancer therapy and other diseases [J].
Dheer, Divya ;
Nicolas, Julien ;
Shankar, Ravi .
ADVANCED DRUG DELIVERY REVIEWS, 2019, 151 :130-151
[10]   Dual Responsive Polymersomes for Gold Nanorod and Doxorubicin Encapsulation: Nanomaterials with Potential Use as Smart Drug Delivery Systems [J].
DiazDuarte-Rodriguez, Melissa ;
Cortez-Lemus, Norma A. ;
Licea-Claverie, Angel ;
Licea-Rodriguez, Jacob ;
Mendez, Eugenio R. .
POLYMERS, 2019, 11 (06)