[Cu(maloNHC)]-catalyzed synthesis of 2-aryl pyrazolo[5,1-a]isoquinolines by annulation of N′-(2-((trimethylsilyflethynyl)benzylidene)hydrazides with terminal aromatic alkynes

被引：11

作者：

Liu, Huixin ^{[1
]}

Lu, Le ^{[1
]}

Hua, Ruimao ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Minist Educ, Beijing 100084, Peoples R China

来源：

TETRAHEDRON | 2017年 / 73卷 / 45期

基金：

中国国家自然科学基金;

关键词：

Annulation; Alkynes; Pyrazolo[5,1-a]isoquinolines; N-heterocyclic carbene; C-H ACTIVATION; ONE-POT APPROACH; PYRAZOLE DERIVATIVES; CASCADE REACTION; BIOLOGICAL EVALUATION; 3+2 CYCLOADDITION; CLICK CHEMISTRY; EFFICIENT; ISOQUINOLINES; CATALYSIS;

D O I：

10.1016/j.tet.2017.09.037

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A [Cu(maioNHC)]-catalyzed synthesis of 2-aryl pyrazolo[5,1-a]isoquinolines via annulation of N'-(2((trimethylsilyl)ethynyl)benzylidene)hydrazides with terminal aromatic alkynes was developed. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：6428 / 6435

页数：8

共 54 条

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