Genome-wide identification, characterization and expression analysis of MATE family genes in apple (Malus x domestica Borkh)

被引：18

作者：

Zhang, Weihan ^{[1
]}

Liao, Liao ^{[2
]}

Xu, Jinsheng ^{[1
]}

Han, Yuepeng ^{[2
]}

Li, Li ^{[1
,3
]}

机构：

[1] Huazhong Agr Univ, Coll Informat, Hubei Key Lab Agr Bioinformat, Wuhan 430070, Peoples R China

[2] Chinese Acad Sci, Innovat Acad Seed Design, CAS Key Lab Plant Germplasm Enhancement & Special, Wuhan Bot Garden, Wuhan 430074, Peoples R China

[3] Huazhong Agr Univ, Hubei Hongshan Lab, Wuhan 430070, Peoples R China

来源：

BMC GENOMICS | 2021年 / 22卷 / 01期

关键词：

Apple; MATE; Gene family; Expression profile; Disease resistance; MULTIDRUG EFFLUX PROTEIN; REGULATORY ELEMENTS; ALUMINUM RESISTANCE; IRON HOMEOSTASIS; TRANSPORTER; ARABIDOPSIS; EVOLUTION; DUPLICATION; CLASSIFICATION; VISUALIZATION;

D O I：

10.1186/s12864-021-07943-1

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Background As an important group of the multidrug efflux transporter family, the multidrug and toxic compound extrusion (MATE) family has a wide range of functions and is distributed in all kingdoms of living organisms. However, only two MATE genes in apple have been analyzed and genome-wide comprehensive analysis of MATE family is needed. Results In this study, a total of 66 MATE (MdMATE) candidates encoding putative MATE transporters were identified in the apple genome. These MdMATE genes were classified into four groups by phylogenetic analysis with MATE genes in Arabidopsis. Synteny analysis reveals that whole genome duplication (WGD) and segmental duplication events played a major role in the expansion of MATE gene family in apple. MdMATE genes show diverse expression patterns in different tissues/organs and developmental stages. Analysis of cis-regulatory elements in MdMATE promoter regions indicates that the function of MdMATE genes is mainly related to stress response. Besides, the changes of gene expression levels upon different pathogen infections reveal that MdMATE genes are involved in biotic stress response. Conclusions In this work, we systematically identified MdMATE genes in apple genome using a set of bioinformatics approaches. Our comprehensive analysis provided valuable resources for improving disease resistance in apple and further functional characterization of MATE genes in other species.

引用

页数：14

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