CoFe2O4 nanoparticle/ionic liquid modified carbon paste electrode as an amplified sensor for epirubicin analysis as an anticancer drug

被引：46

作者：

Karimi, Fatemeh ^{[1
]}

Shojaei, Abdollah Fallah ^{[2
]}

Tabatabaeian, Khalil ^{[2
]}

Shakeri, Shahryar ^{[3
]}

机构：

[1] Univ Guilan, Pardis Campus,POB 1841, Rasht, Iran

[2] Univ Guilan, Dept Chem, Fac Sci, POB 1914, Rasht, Iran

[3] Grad Univ Adv Technol, Inst Sci & High Technol & Environm Sci, Dept Biotechnol, Kerman, Iran

来源：

JOURNAL OF MOLECULAR LIQUIDS | 2017年 / 242卷

关键词：

Epirubicin; 1,3-Dipropylimidazolium bromide; CoFe2O4; nanoparticle; Anticancer drug; NANOSTRUCTURE VOLTAMMETRIC SENSOR; TEMPERATURE IONIC LIQUID; ASCORBIC-ACID; ELECTROCHEMICAL SENSOR; URIC-ACID; NANOTUBES APPLICATION; DOPAMINE; PERFORMANCE; CATECHOLAMINES; CHROMATOGRAPHY;

D O I：

10.1016/j.molliq.2017.07.067

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A suitable amount of CoFe2O4 nanoparticle (CoFe2O4/NPs) was used for modification of carbon paste electrode in the presence of paraffin oil and 1,3-dipropylimidazolium bromide (1,3-DPIBr) as binders. The modified electrode showed highly catalytic activity for electro-oxidation of epirubicin in biological condition. CoFe2O4 nanoparticle were synthesized by co-precipitation method with diameter of similar to 17.0 nm and characterized with XRD and TEM methods. The chronoamperometry method was used to evaluate diffusion coefficient (D-app) of the epirubicin in phosphate buffer solution pH = 7.0. A calibration curve with sensitivity (0.1426 mu A/mu M) was obtained for epirubicin in the concentration range 0.04-450 mu M at a surface of proposed electrode. Finally, the amplified sensor showed good ability of analysis of epirubicin in injection and serum samples. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：685 / 689

页数：5

共 45 条

[1] Electrochemical determination of vitamin C in the presence of NADH using a CdO nanoparticle/ionic liquid modified carbon paste electrode as a sensor [J].