Update on the management of overactive bladder

被引:28
作者
Fontaine, Christina [1 ]
Papworth, Emma [2 ]
Pascoe, John [3 ]
Hashim, Hashim [2 ]
机构
[1] Univ Hosp Plymouth, Urol, Derriford Rd, Plymouth PL6 8AU, Devon, England
[2] Southmead Hosp, Bristol Urol Inst, Bristol, Somerset, England
[3] Univ Hosp Plymouth, Plymouth, Devon, England
关键词
antimuscarinic; beta-agonist; BOTOX; overactive bladder; sacral neuromodulation; urinary incontinence; TIBIAL NERVE-STIMULATION; DETRUSOR OVERACTIVITY; DOUBLE-BLIND; AUGMENTATION CYSTOPLASTY; EFFICACY; MIRABEGRON; PLACEBO; NEUROMODULATION; INCONTINENCE; SYMPTOMS;
D O I
10.1177/17562872211039034
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Overactive bladder (OAB) syndrome is a common condition characterised by urinary urgency, with or without urgency incontinence, frequency and nocturia, in the absence of any other pathology. Clinical diagnosis is based upon patient self-reported symptomology. Currently there is a plethora of treatments available for the management of OAB. Clinical guidelines suggest treatment via a multidisciplinary pathway including behavioural therapy and pharmacotherapy, which can be commenced in primary care, with referral to specialist services in those patients refractory to these treatments. Intradetrusor botulinum A and sacral neuromodulation provide safe and efficacious management of refractory OAB. Percutaneous tibial nerve stimulation and augmentation cystoplasty remain available and efficacious in a select group of patients. Unfortunately, there remains a high rate of patient dissatisfaction and discontinuation in all treatments and thus there remains a need for emerging therapies in the management of OAB.
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页数:9
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