Bio-bar-code dendrimer-like DNA as signal amplifier for cancerous cells assay using ruthenium nanoparticle-based ultrasensitive chemiluminescence detection

被引:42
作者
Bi, Sai [1 ]
Hao, Shuangyuan [1 ]
Li, Li [1 ]
Zhang, Shusheng [1 ]
机构
[1] Qingdao Univ Sci & Technol, Key Lab Ecochem Engn, Minist Educ, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China
基金
中国国家自然科学基金;
关键词
FLUORESCENCE NANOBARCODES; DELIVERY; POLYMER;
D O I
10.1039/c0cc01409e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Bio-bar-code dendrimer-like DNA (bbc-DL-DNA) is employed as a label for the amplification assay of cancer cells in combination with the newly explored chemiluminescence (CL) system of luminol-H(2)O(2)-Ru(3+) and specificity of structure-switching aptamers selected by cell-based SELEX.
引用
收藏
页码:6093 / 6095
页数:3
相关论文
共 28 条
[1]   Bifunctional Dendrimers: From Robust Synthesis and Accelerated One-Pot Postfunctionalization Strategy to Potential Applications [J].
Antoni, Per ;
Hed, Yvonne ;
Nordberg, Axel ;
Nystrom, Daniel ;
von Holst, Hans ;
Hult, Anders ;
Malkoch, Michael .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (12) :2126-2130
[2]   Metal-enhanced chemiluminescence: advanced chemiluminescence concepts for the 21st century [J].
Aslan, Kadir ;
Geddes, Chris D. .
CHEMICAL SOCIETY REVIEWS, 2009, 38 (09) :2556-2564
[3]   Bio-bar-code functionalized magnetic nanoparticle label for ultrasensitive flow injection chemiluminescence detection of DNA hybridization [J].
Bi, Sai ;
Zhou, Hong ;
Zhang, Shusheng .
CHEMICAL COMMUNICATIONS, 2009, (37) :5567-5569
[4]   Dendrimers and DNA: Combinations of two special topologies for nanomaterials and biology [J].
Caminade, Anne-Marie ;
Turrin, Cedric-Olivier ;
Majoral, Jean-Pierre .
CHEMISTRY-A EUROPEAN JOURNAL, 2008, 14 (25) :7422-7432
[5]  
Capaldi S, 2000, Nucleic Acids Res, V28, pE21, DOI 10.1093/nar/28.7.e21
[6]   Using Aptamer-Conjugated Fluorescence Resonance Energy Transfer Nanoparticles for Multiplexed Cancer Cell Monitoring [J].
Chen, Xiaolan ;
Estevez, M. -Carmen ;
Zhu, Zhi ;
Huang, Yu-Fen ;
Chen, Yan ;
Wang, Lin ;
Tan, Weihong .
ANALYTICAL CHEMISTRY, 2009, 81 (16) :7009-7014
[7]   Synthesis, characterization, and electrochemiluminescence of luminol-reduced gold nanoparticles and their application in a hydrogen peroxide sensor [J].
Cui, Hua ;
Wang, Wei ;
Duan, Chun-Feng ;
Dong, Yong-Ping ;
Guo, Ji-Zhao .
CHEMISTRY-A EUROPEAN JOURNAL, 2007, 13 (24) :6975-6984
[8]   Dendritic DNA Building Blocks for Amplified Detection Assays and Biomaterials [J].
Feldkamp, Udo ;
Sacca, Barbara ;
Niemeyer, Christof M. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (33) :5996-6000
[9]   Diffusion of single star-branched dendrimer-like DNA [J].
Freedman, KO ;
Lee, J ;
Li, YG ;
Luo, D ;
Skobeleva, VB ;
Ke, PC .
JOURNAL OF PHYSICAL CHEMISTRY B, 2005, 109 (19) :9839-9842
[10]   Magnetic nanoparticles: synthesis, functionalization, and applications in bioimaging and magnetic energy storage [J].
Frey, Natalie A. ;
Peng, Sheng ;
Cheng, Kai ;
Sun, Shouheng .
CHEMICAL SOCIETY REVIEWS, 2009, 38 (09) :2532-2542