Rh(iii)-Catalyzed regioselective C-H [4+2] C-annulation of vinyl enaminones with alkynes to form polysubstituted salicylaldehydes

被引：26

作者：

Zhao, Yinsong ^{[1
]}

Zheng, Qinze ^{[1
]}

Yu, Chuangui ^{[1
]}

Liu, Zheng ^{[1
]}

Wang, Deping ^{[1
]}

You, Jingsong ^{[1
]}

Gao, Ge ^{[1
]}

机构：

[1] Sichuan Univ, Coll Chem, Minist Educ, Key Lab Green Chem & Technol, 29 Wangjiang Rd, Chengdu 610064, Sichuan, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2018年 / 5卷 / 19期

关键词：

BOND ACTIVATION; CATALYZED CYCLIZATION; ORTHO-FORMYLATION; INTERNAL ALKYNES; ARYL TOSYLATES; O-ANNULATION; PHENOLS; FUNCTIONALIZATION; DERIVATIVES; CARBAZOLES;

D O I：

10.1039/c8qo00759d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A Rh(iii)-catalyzed regioselective C-H [4 + 2] C-annulation reaction of vinyl enaminones with alkynes is developed to provide sterically congested polysubstituted salicylaldehydes. This reaction shows relatively broad substrate scope with good functional group tolerance. The applications of this method to prepare useful synthetic precursors and bioactive skeletons are also exemplified.

引用

页码：2875 / 2879

页数：5

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