HIV-1 and Breastfeeding: Biology of Transmission and Advances in Prevention

被引：17
作者：
Bulterys, Marc [1 ,2 ]
Ellington, Sascha [3 ]
Kourtis, Athena P. [3 ]
机构：
[1] Ctr Dis Control & Prevent CDC, Div HIV AIDS, Ctr Global Hlth, Atlanta, GA 30333 USA
[2] CDC Global AIDS Program, Beijing, Peoples R China
[3] Ctr Dis Control & Prevent, Div Reprod Hlth, Natl Ctr Chron Dis Preventat & Hlth Promot, Atlanta, GA 30341 USA
来源：
CLINICS IN PERINATOLOGY | 2010年 / 37卷 / 04期
关键词：
Breastfeeding; HIV-1; Mother-to-child HIV transmission; Antiretroviral prophylactic treatment; HUMAN-IMMUNODEFICIENCY-VIRUS; TO-CHILD TRANSMISSION; SHORT-COURSE ZIDOVUDINE; RNA VIRAL LOAD; DAR-ES-SALAAM; POSTNATAL TRANSMISSION; ANTIRETROVIRAL THERAPY; VERTICAL TRANSMISSION; HIV-1-INFECTED WOMEN; MILK CELLS;
D O I：
10.1016/j.clp.2010.08.001
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Breastfeeding accounts for about 40% of mother-to-child transmission of HIV-1 worldwide and carries an estimated risk of transmission of 0.9% per month after the first month of breastfeeding. It is recommended that HIV-1-infected women completely avoid breastfeeding in settings where safe feeding alternatives exist. However, as replacement feeding is not safely available in many parts of the world, and because breastfeeding provides optimal nutrition and protection against other infant infections, there is intense ongoing research to make breastfeeding safe for HIV-1-infected mothers in resource-limited settings. More research is needed to determine the optimal duration of breastfeeding, optimal weaning practices, and which individual antiretroviral prophylactic regimen is best for HIV-1-infected mothers and their infants in a particular setting.
引用
收藏
页码：807 / +
页数：20
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