Synthesis of N-arylsulfonyl-α-thienylglycines from N-(2,2,2-trichloro-1-thienylethyl)arenesulfonamides

被引：2

作者：

Aizina, YA ^{[1
]}

Rozentsveig, IB ^{[1
]}

Ushakova, IV ^{[1
]}

Levkovskaya, GG ^{[1
]}

Mirskova, AN ^{[1
]}

机构：

[1] Russian Acad Sci, Favorskii Irkutsk Inst Chem, Siberian Div, Irkutsk 664033, Russia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 41卷 / 01期

关键词：

Hydrolysis; Organic Chemistry; Thiophene; Alkaline Hydrolysis; Trichloromethyl;

D O I：

10.1007/s11178-005-0126-x

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reactions of N-(2,2,2-trichloroethylidene)arenesulfonamides with thiophene, 2-chlorothiophene, and 2,5-dichlorothiophene, as well as of N-(2,2,2-trichloro-1-hydroxyethyl)arenesulfonamides with 2-chlorothiophene, lead to formation of the corresponding N-(2,2,2-trichloro-1-thienylethyi)arenesulfonamides. Alkaline hydrolysis of the latter occurs selectively at the trichloromethyl group to give N-arylsulfonyl-alpha-thienylglycines.

引用

页码：91 / 94

页数：4