Intracavitary physiotherapy is not inferior to endometrial scratching in patients with recurrent implantation failure

被引:8
作者
Zhang, Qian [1 ,2 ,3 ,4 ]
Zhang, Bo [1 ,5 ]
Yan, Junhao [1 ,2 ,3 ,4 ]
Zhang, Chu [1 ,2 ,3 ,4 ]
Tang, Rong [1 ,2 ,3 ,4 ]
Sheng, Yan [1 ,2 ,3 ,4 ]
Wang, Na [1 ,2 ,3 ,4 ]
Chen, Zi-Jiang [1 ,2 ,3 ,4 ,6 ,7 ]
机构
[1] Shandong Univ, Shandong Prov Hosp, Ctr Reprod Med, Jinan 250021, Peoples R China
[2] Natl Res Ctr Assisted Reprod Technol & Reprod Gen, Jinan, Peoples R China
[3] Minist Educ, Key Lab Reprod Endocrinol, Jinan, Peoples R China
[4] Shandong Prov Key Lab Reprod Med, Jinan, Peoples R China
[5] Wuhan Univ, Zhongnan Hosp, Reprod Med Ctr, Wuhan 430072, Peoples R China
[6] Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Shanghai 200030, Peoples R China
[7] Shanghai Key Lab Assisted Reprod & Reprod Genet, Shanghai, Peoples R China
关键词
Recurrent implantation failure; Endometrium receptivity; Intracavitary physiotherapy; Endometrial scratching; LOCAL INJURY; MOLECULAR-INTERACTIONS; IMPROVES IMPLANTATION; SPERM INJECTION; PREGNANCY RATE; EMBRYO; UTERUS;
D O I
10.1007/s00404-014-3382-6
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
To investigate whether intracavitary physiotherapy is superior to endometrial scratching in patients with recurrent implantation failure (RIF) after in vitro fertilization/intracytoplasmic sperm injection- embryo transfer (IVF/ICSI-ET) cycles. According to the inclusion criteria defined by our hospital, 63 patients with RIF were included in the retrospective study. 20 patients who received intracavitary physiotherapy were classified into Group A, 8 patients with both intracavitary physiotherapy and endometrial scratching were into Group B, and 35 patients who underwent endometrial scratching were into Group C. The primary outcome measures were implantation and clinical pregnancy rates. The secondary outcome measure was pregnancy outcome. There were no statistical differences in implantation and clinical pregnancy rates between Groups A and C (29.41 vs 35.59 %, 45.00 vs 48.57 % respectively, P > 0.05), Groups B and C (36.36 vs 35.59 %, 50.00 vs 48.57 % respectively, P > 0.05). In addition, no statistical differences were discovered in pregnancy outcomes between Groups A and C (P > 0.05), Groups B and C (P > 0.05). Intracavitary physiotherapy is not inferior to endometrial scratching on improving implantation and clinical pregnancy rates in patients with RIF after IVF/ICSI cycles.
引用
收藏
页码:173 / 177
页数:5
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