Nickel-Catalyzed Intermolecular [2+2] Cycloaddition of Conjugated Enynes with Alkenes

被引：115

作者：

Nishimura, Akira ^{[1
]}

Ohashi, Masato ^{[1
]}

Ogoshi, Sensuke ^{[1
]}

机构：

[1] Osaka Univ, Dept Appl Chem, Fac Engn, Suita, Osaka 5650871, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2012年 / 134卷 / 38期

关键词：

SILYL ENOL ETHERS; DIMETHYL ACETYLENEDICARBOXYLATE; CYCLOISOMERIZATION REACTIONS; NORBORNENE DERIVATIVES; REDUCTIVE ELIMINATION; ETHYL PROPIOLATE; COBALT COMPLEXES; ALKYNES; ESTERS; CYCLOBUTENES;

D O I：

10.1021/ja3074775

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A nickel-catalyzed intermolecular [2 + 2] cycloaddition of conjugated enynes with alkenes has been developed. A variety of electron-deficient alkenes as well as electronically neutral norbornene and 1-decene were applicable to this reaction. The use of conjugated enynes circumvented possible side rections, such as oligomerizations and cyclotrimerizations. The isolation of reaction intermediate complexes revealed that the eta(3)-butadienyl coordination is the key for the selective formation of cyclobutene.

引用

页码：15692 / 15695

页数：4

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