Nickel-Catalyzed Intermolecular [2+2] Cycloaddition of Conjugated Enynes with Alkenes

被引：113
|
作者：
Nishimura, Akira [1 ]
Ohashi, Masato [1 ]
Ogoshi, Sensuke [1 ]
机构：
[1] Osaka Univ, Dept Appl Chem, Fac Engn, Suita, Osaka 5650871, Japan
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2012年 / 134卷 / 38期
关键词：
SILYL ENOL ETHERS; DIMETHYL ACETYLENEDICARBOXYLATE; CYCLOISOMERIZATION REACTIONS; NORBORNENE DERIVATIVES; REDUCTIVE ELIMINATION; ETHYL PROPIOLATE; COBALT COMPLEXES; ALKYNES; ESTERS; CYCLOBUTENES;
D O I：
10.1021/ja3074775
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A nickel-catalyzed intermolecular [2 + 2] cycloaddition of conjugated enynes with alkenes has been developed. A variety of electron-deficient alkenes as well as electronically neutral norbornene and 1-decene were applicable to this reaction. The use of conjugated enynes circumvented possible side rections, such as oligomerizations and cyclotrimerizations. The isolation of reaction intermediate complexes revealed that the eta(3)-butadienyl coordination is the key for the selective formation of cyclobutene.
引用
收藏
页码：15692 / 15695
页数：4
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