A radical scavenging farnesylhydroquinone from a marine-derived fungus Penicillium sp.

被引:22
作者
Son, BW [1 ]
Kim, JC
Choi, HD
Kang, JS
机构
[1] Pukyong Natl Univ, Dept Chem, Pusan 608737, South Korea
[2] Dongeui Univ, Dept Chem, Pusan 614714, South Korea
[3] Pusan Natl Univ, Dept Oral Biochem & Mol Biol, Pusan 602739, South Korea
关键词
marine fungus; Penicillium sp; sesquiterpene quinone; farnesylhydroquinone; radical scavenging; DPPH;
D O I
10.1007/BF02975266
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Farnesylhydroquinone (1) has been isolated from the mycelium of a marine-derived fungus of the genus Penicillium. The structure of the compound (1) has been elucidated by spectral method. The compound 1 exhibits potent radical scavenging activity (IC50 12.5 muM) against the DPPH.
引用
收藏
页码:77 / 79
页数:3
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