Anti-DNA autoantibodies: a puzzle of autoimmune phenomena

被引：22

作者：

Eilat, D ^{[1
]}

Naparstek, Y ^{[1
]}

机构：

[1] Hadassah Univ Hosp, Div Med, Clin Immunol Unit, IL-91120 Jerusalem, Israel

来源：

IMMUNOLOGY TODAY | 1999年 / 20卷 / 08期

关键词：

D O I：

10.1016/S0167-5699(99)01457-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The role of anti-DNA antibodies in the pathogenesis of SLE is as yet unknown. A recent workshop* discussed the maintenance and loss of immune tolerance to DNA and evaluated navel research directions, most notably anti-DNA transgenic mice.

引用

页码：339 / 342

页数：4

共 15 条

[1] ANTIBODY TO NUCLEAR RIBONUCLEOPROTEIN PENETRATES LIVE HUMAN MONONUCLEAR-CELLS THROUGH FC RECEPTORS [J].

ALARCONSEGOVIA, D ;

RUIZARGUELLES, A ;

FISHBEIN, E .

NATURE, 1978, 271 (5640) :67-69

[2] STRUCTURE-FUNCTION CORRELATES OF AUTOANTIBODIES TO NUCLEIC-ACIDS - LESSONS FROM IMMUNOCHEMICAL, GENETIC AND STRUCTURAL STUDIES [J].

EILAT, D ;

ANDERSON, WF .

MOLECULAR IMMUNOLOGY, 1994, 31 (18) :1377-1390

[3]

EILAT D, 1988, J IMMUNOL, V141, P1745

[4] EXPRESSION OF ANTI-DNA IMMUNOGLOBULIN TRANSGENES IN NON-AUTOIMMUNE MICE [J].

ERIKSON, J ;

RADIC, MZ ;

CAMPER, SA ;

HARDY, RR ;

CARMACK, C ;

WEIGERT, M .

NATURE, 1991, 349 (6307) :331-334

[5] RECEPTOR EDITING - AN APPROACH BY AUTOREACTIVE B-CELLS TO ESCAPE TOLERANCE [J].

GAY, D ;

SAUNDERS, T ;

CAMPER, S ;

WEIGERT, M .

JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 177 (04) :999-1008

[6] AN AUTOANTIBODY TO SINGLE-STRANDED-DNA - COMPARISON OF THE 3-DIMENSIONAL STRUCTURES OF THE UNLIGANDED FAB AND A DEOXYNUCLEOTIDE FAB COMPLEX [J].

HERRON, JN ;

HE, XM ;

BALLARD, DW ;

BLIER, PR ;

PACE, PE ;

BOTHWELL, ALM ;

VOSS, EW ;

EDMUNDSON, AB .

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 1991, 11 (03) :159-175

[7] Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus [J].

Kaliyaperumal, A ;

Mohan, C ;

Wu, W ;

Datta, SK .

JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (06) :2459-2469

[8] SELECTION OF IMMUNOGLOBULIN VARIABLE REGIONS IN AUTOIMMUNITY TO DNA [J].

MARION, TN ;

TILLMAN, DM ;

JOU, NT ;

HILL, RJ .

IMMUNOLOGICAL REVIEWS, 1992, 128 :123-149

[9] Immune activation by bacterial DNA: A new genetic code [J].

Pisetsky, DS .

IMMUNITY, 1996, 5 (04) :303-310

[10]

RADIC MZ, 1994, ANNU REV IMMUNOL, V12, P487, DOI 10.1146/annurev.iy.12.040194.002415

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