Early-onset breast cancer in a woman with Graves' disease

被引:0
作者
Siegler, James E. [1 ]
Li, Xinying [2 ]
Jones, Steven D. [3 ]
Kandil, Emad [4 ]
机构
[1] Tulane Univ, Sch Med, New Orleans, LA 70112 USA
[2] Cent S Univ, Xiangya Hosp, Dept Gen Surg, Changsha, Hunan, Peoples R China
[3] Tulane Sch Med, Dept Surg, New Orleans, LA USA
[4] Tulane Univ, Sch Med, Dept Surg, Div Endocrine & Oncol Surg, New Orleans, LA 70112 USA
关键词
Graves' disease; thyroid hormone; estrogen; breast cancer; THYROID-HORMONE; ESTROGEN;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The relationship between thyroid and breast diseases has been documented, but the clinical significance of Graves' disease and breast cancer is unclear. We present a young patient with a history of Graves' disease who developed a multicentric infiltrating ductal carcinoma of the breast several months after discontinuing her treatment with propylthiouracil. Early-onset breast cancer in women without a family history of early breast cancer may be related to hyperthyroidism. The relationship between thyroid hormone and estrogen is discussed.
引用
收藏
页码:358 / 362
页数:5
相关论文
共 10 条
[1]   Thyroid hormone and breast carcinoma - Primary hypothyroidism is associated with a reduced incidence of primary breast carcinoma [J].
Cristofanilli, M ;
Yamamura, Y ;
Kau, SW ;
Bevers, T ;
Strom, S ;
Patangan, M ;
Hsu, LM ;
Krishnamurthy, S ;
Theriault, RL ;
Hortobagyi, GN .
CANCER, 2005, 103 (06) :1122-1128
[2]   Estrogen-like effects of thyroid hormone on the regulation of tumor suppressor proteins, p53 and retinoblastoma, in breast cancer cells [J].
Dinda, S ;
Sanchez, A ;
Moudgil, V .
ONCOGENE, 2002, 21 (05) :761-768
[3]   Relationship between breast cancer and thyroid disease: Relevance of autoimmune thyroid disorders in breast malignancy [J].
Giani, C ;
Fierabracci, P ;
Bonacci, R ;
Gigliotti, A ;
Campani, D ;
DeNegri, F ;
Cecchetti, D ;
Martino, E ;
Pinchera, A .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1996, 81 (03) :990-994
[4]   Effects of thyroid hormones on human breast cancer cell proliferation [J].
Hall, Linda C. ;
Salazar, Eddie P. ;
Kane, Staci R. ;
Liu, Nan .
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2008, 109 (1-2) :57-66
[5]  
ITOH K, 1975, LANCET, V2, P1119
[6]   INCIDENCE OF MALIGNANT NEOPLASMS OF ALL TYPES IN PATIENTS WITH GRAVES-DISEASE [J].
MUNOZ, JM ;
GORMAN, CA ;
ELVEBACK, LR ;
WENTZ, JR .
ARCHIVES OF INTERNAL MEDICINE, 1978, 138 (06) :944-947
[7]   Triiodothyronine mimics the effects of estrogen in breast cancer cell lines [J].
Nogueira, CR ;
Brentani, MM .
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1996, 59 (3-4) :271-279
[8]   RADICAL MASTECTOMY IN A PATIENT WITH COEXISTENT GRAVES-DISEASE [J].
STARLING, JR ;
THOMAS, CG .
AMERICAN JOURNAL OF SURGERY, 1976, 132 (01) :110-111
[9]   Thyroid hormone causes mitogen-activated protein kinase-dependent phosphorylation of the nuclear estrogen receptor [J].
Tang, HY ;
Lin, HY ;
Zhang, SL ;
Davis, FB ;
Davis, PJ .
ENDOCRINOLOGY, 2004, 145 (07) :3265-3272
[10]   Ligand-dependent cross-talk between steroid and thyroid hormone receptors - Evidence for common transcriptional coactivator(s) [J].
Zhang, X ;
Jeyakumar, M ;
Bagchi, MK .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (25) :14825-14833