Assessment of fat-free mass from bioelectrical impedance analysis in men and women with Prader-Willi syndrome: cross-sectional study

被引:11
作者
Bedogni, Giorgio [1 ,2 ]
Grugni, Graziano [3 ]
Tringali, Gabriella [4 ,5 ]
Tamini, Sofia [4 ,5 ]
Marzullo, Paolo [6 ,7 ]
Sartorio, Alessandro [3 ,4 ,5 ]
机构
[1] Liver Res Ctr, Clin Epidemiol Unit, Bldg Q,AREA Sci Pk,Str Statale 14 Km 163-5, I-34012 Trieste, Italy
[2] Univ Milan, ICANS, Milan, Italy
[3] Ist Auxol Italiano, IRCCS, Div Auxol & Metab Dis, Oggebbio, VB, Italy
[4] Ist Auxol Italiano, IRCCS, Expt Lab Auxoendocrinol Res, Milan, Italy
[5] Ist Auxol Italiano, IRCCS, Expt Lab Auxoendocrinol Res, Oggebbio, VB, Italy
[6] Ist Auxol Italiano, IRCCS, Div Gen Med, Oggebbio, VB, Italy
[7] Univ Piemonte Orientale, Dept Translat Med, Novara, Italy
关键词
Bioelectrical impedance analysis; body composition; dual energy X-ray absorptiometry; Prader-Willi syndrome; prediction equations; X-RAY ABSORPTIOMETRY; BODY-COMPOSITION; DISEASE;
D O I
10.1080/09637486.2018.1554623
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
We have recently shown that population-specific formulae are required to estimate fat-free mass (FFM) from bioelectrical impedance analysis (BIA) in obese women with Prader-Willi syndrome (PWS) matched by age and percent fat mass (FM) to non-PWS women. The present cross-sectional study was aimed at developing generalised BIA equations that could be used in PWS subjects independently of sex and FM. We used dual-energy X-ray absorptiometry to measure FFM and BIA to measure whole-body impedance at 50 kHz (Z(50)) in 34 women and 21 men with PWS. The impedance index, that is, height (cm)(2)/Z(50) (omega), explained 77% (BCa-bootstrapped 95% CI 65 to 85%) of the variance of FFM with a root mean squared error of the estimate of 3.7 kg (BCa-bootstrapped 95% CI 3.2 to 4.5 kg). BIA can be used to estimate FFM in obese and non-obese PWS men and women by means of population-specific equations.
引用
收藏
页码:645 / 649
页数:5
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