TMS-OTf-catalyzed α-bromination of carbonyl compounds by N-bromosuccinimide

被引：44

作者：

Guha, SK ^{[1
]}

Wu, B ^{[1
]}

Kim, BS ^{[1
]}

Baik, W ^{[1
]}

Koo, S ^{[1
]}

机构：

[1] Myong Ji Univ, Dept Chem, Yongin 449728, Kyunggi, South Korea

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 03期

关键词：

D O I：

10.1016/j.tetlet.2005.11.023

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various carbonyl compounds undergo alpha-bromination reaction under a mild and practical condition utilizing N-bromosuccinimide (NBS), catalyzed by trimethylsilyl trifluoromethanesulfonate ((TMSOTf)-O-.). This method is also effective for the side-chain bromination of heteroaromatic carbonyl compounds without the ring brominations. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：291 / 293

页数：3

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