Comparison of two optical techniques for label-free detection of biomolecular microarrays on solids

被引:19
|
作者
Zhu, XD [1 ]
机构
[1] Univ Calif Davis, Dept Phys, NSF, Ctr Biophoton Sci & Technol, Davis, CA 95616 USA
关键词
D O I
10.1016/j.optcom.2005.09.079
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
I compare two techniques for label-free detection of biomolecular reactions on solid supports in microarray format. I show that the oblique-incidence reflectivity difference (OI-RD), when operated near the Brewster angle, is as sensitivity as the surface plasmon resonance technique. The OI-RD technique is more versatile and promises higher throughputs. (C) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:751 / 753
页数:3
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