The role of Rsp5 ubiquitin ligase in regulation of diverse processes in yeast cells

被引：0

作者：

Kaliszewski, Pawel ^{[1
]}

Zoladek, Teresa ^{[1
]}

机构：

[1] Polish Acad Sci, Inst Biochem & Biophys, Dept Genet, PL-02106 Warsaw, Poland

来源：

ACTA BIOCHIMICA POLONICA | 2008年 / 55卷 / 04期

关键词：

Rsp5; ubiquitin ligase; Spt23; Mga2; transcriptional activators; ubiquitination; Saccharomyces cerevisiae;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Rsp5 is a conserved ubiquitin ligase involved in regulation of numerous cellular processes. A growing number of publications describing new functions of the ligase have appeared in recent years. Rsp5 was shown to be involved in the control of intracellular trafficking of proteins via endocytosis and multivesicular body sorting. Moreover, nuclear functions of Rsp5 in response to various stresses have been discovered. Rsp5 is also involved in the regulation of unsaturated fatty acid and sterol synthesis and phospholipid composition. Here, an overview of Rsp5 functions with emphasis on its involvement in the regulation of lipid biosynthesis will be presented.

引用

页码：649 / 662

页数：14

共 161 条

[1] Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae [J].

Agarwal, AK ;

Rogers, PD ;

Baerson, SR ;

Jacob, MR ;

Barker, KS ;

Cleary, JD ;

Walker, LA ;

Nagle, DG ;

Clark, AM .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (37) :34998-35015

[2] Histone modification governs the cell cycle regulation of a replication-independent chromatin assembly pathway in Saccharomyces cerevisiae [J].

Altheim, BA ;

Schultz, MC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (04) :1345-1350

[3] STRESS RESISTANCE IN SACCHAROMYCES-CEREVISIAE IS STRONGLY CORRELATED WITH ASSEMBLY OF A NOVEL TYPE OF MULTIUBIQUITIN CHAIN [J].

ARNASON, T ;

ELLISON, MJ .

MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (12) :7876-7883

[4] Novel interaction between Apc5p and Rsp5p in an intracellular signaling pathway in Saccharomyces cerevisiae [J].

Arnason, TG ;

Pisclevich, MG ;

Dash, MD ;

Davies, GF ;

Harkness, TAA .

EUKARYOTIC CELL, 2005, 4 (01) :134-146

[5]

ASHBY MN, 1992, J BIOL CHEM, V267, P4128

[6]

ASHBY MN, 1990, J BIOL CHEM, V265, P13157

[7] Genomic association of the proteasome demonstrates overlapping gene regulatory activity with transcription factor substrates [J].

Auld, KL ;

Brown, CR ;

Casolari, JM ;

Komili, S ;

Silver, PA .

MOLECULAR CELL, 2006, 21 (06) :861-871

[8] Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast [J].

Bagnat, M ;

Keränen, S ;

Shevchenko, A ;

Simons, K .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (07) :3254-3259

[9] Genome-wide expression patterns in Saccharomyces cerevisiae:: Comparison of drug treatments and genetic alterations affecting biosynthesis of ergosterol [J].

Bammert, GF ;

Fostel, JM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (05) :1255-1265

[10]

Beaudenon SL, 1999, MOL CELL BIOL, V19, P6972

← 1 2 3 4 5 6 7 8 9 10 →