Precision Control of Temperature Response by Copolymerization of Di(Ethylene Glycol) Acrylate and an Acrylamide Comonomer

被引：49
作者：
De, Priyadarsi [1 ]
Sumerlin, Brent S. [2 ,3 ]
机构：
[1] Indian Inst Sci Educ & Res, Polymer Res Ctr, Dept Chem Sci, Nadia 741252, W Bengal, India
[2] So Methodist Univ, Dept Chem, Dallas, TX 75275 USA
[3] Univ Florida, George & Josephine Butler Polymer Res Lab, Ctr Macromol Sci & Engn, Dept Chem, Gainesville, FL 32611 USA
来源：
MACROMOLECULAR CHEMISTRY AND PHYSICS | 2013年 / 214卷 / 02期
基金：
美国国家科学基金会;
关键词：
block copolymers; cloud point; hydrodynamic diameter; lower critical solution temperature; RAFT polymerization; FRAGMENTATION CHAIN TRANSFER; THERMORESPONSIVE POLYMERS; FLUORESCENT PH; DRUG-DELIVERY; RAFT; BEHAVIOR; POLYMERIZATION; METHACRYLATES; LCST; NANOPARTICLES;
D O I：
10.1002/macp.201200416
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The readily tuned thermoresponsive behavior of well-defined statistical and block copolymers of di(ethylene glycol)ethyl ether acrylate (DEGA) and N,N-dimethylacrylamide (DMA) was investigated. DEGA and DMA were copolymerized with various comonomer feed ratios by reversible additionfragmentation chain transfer (RAFT) polymerization. Reactivity ratios were determined, which allowed copolymers with precisely tuned compositions to be prepared. The cloud point of the resulting copolymers was observed to vary linearly with the mole fraction of hydrophilic DMA over the range of 1090 degrees C. Block copolymers of DEGA were also prepared by chain extension of poly(DEGA) homopolymers with DMA. The resulting block copolymers formed well-defined polymeric micelles when heated above the cloud point of the poly(DEGA) block. Thus, copolymerization of DEGA was shown to be a convenient route to thermoresponsive polymers with specific and predictable transition temperatures.
引用
收藏
页码：272 / 279
页数：8
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