Recent advances in the treatment of colon cancer

被引：1
作者：
Xu, R [1 ]
Zhou, B
Fung, PCW
Li, X
机构：
[1] Huaqiao Univ, Inst Mol Med, Fujian 362021, Peoples R China
[2] Univ Hong Kong, Gene Therapy Lab, GRC, Hong Kong, Hong Kong, Peoples R China
[3] Univ Hong Kong, Dept Med, Hong Kong, Hong Kong, Peoples R China
来源：
HISTOLOGY AND HISTOPATHOLOGY | 2006年 / 21卷 / 08期
关键词：
colon cancer; chemotherapy; immunotherapy; apoptosis; angiogenesis;
D O I：
暂无
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Colorectal cancer is one of the leading causes of cancer-related deaths worldwide. Although surgical resection is still the only treatment capable of curing colon cancer, adjuvant therapy continues to play an important role in preventing recurrence and metastasis. In recent years remarkable progress has been made in the treatment of colon cancer. This review discusses recent advances in adjuvant therapy for colon cancer, including chemotherapy, immunotherapy, antiangiogenic therapy and apoptosis induction. In the meantime, molecular therapy is also elucidated in the above methods. All these new advances will provide new promises for patients of colon cancer.
引用
收藏
页码：867 / 872
页数：6
相关论文
共 57 条
[1]   REQUIREMENT OF VASCULAR INTEGRIN ALPHA(V)BETA(3) FOR ANGIOGENESIS [J].
BROOKS, PC ;
CLARK, RAF ;
CHERESH, DA .
SCIENCE, 1994, 264 (5158) :569-571
[2]  
Campos F. G., 2005, Nutr. Hosp., V20, P18
[3]   Effect of bone marrow-derived monocytes transfected with RNA of mouse colon carcinoma on specific antitumor immunity [J].
Chu, Xiao-Yuan ;
Chen, Long-Bang ;
Zang, Jing ;
Wang, Jing-Hua ;
Zhang, Qun ;
Geng, Huai-Cheng .
WORLD JOURNAL OF GASTROENTEROLOGY, 2005, 11 (05) :760-763
[4]   Nitric oxide and ionizing radiation synergistically promote apoptosis and growth inhibition of cancer by activating p53 [J].
Cook, T ;
Wang, Z ;
Alber, S ;
Liu, KH ;
Watkins, SC ;
Vodovotz, Y ;
Billiar, TR ;
Blumberg, D .
CANCER RESEARCH, 2004, 64 (21) :8015-8021
[5]   From bench to bedside for gene-directed enzyme prodrug therapy of cancer [J].
Dachs, GU ;
Tupper, J ;
Tozer, GM .
ANTI-CANCER DRUGS, 2005, 16 (04) :349-359
[6]  
DeVita VT., 2001, CANC PRINCIPLES PRAC
[7]   Endostatin exhibits a direct antitumor effect in addition to its antiangiogenic activity in colon cancer cells [J].
Dkhissi, F ;
Lu, H ;
Soria, C ;
Opolon, P ;
Griscelli, F ;
Liu, HF ;
Khattar, P ;
Mishal, Z ;
Perricaudet, M ;
Li, H .
HUMAN GENE THERAPY, 2003, 14 (10) :997-1008
[8]   UP-REGULATION OF CYCLOOXYGENASE-2 GENE-EXPRESSION IN HUMAN COLORECTAL ADENOMAS AND ADENOCARCINOMAS [J].
EBERHART, CE ;
COFFEY, RJ ;
RADHIKA, A ;
GIARDIELLO, FM ;
FERRENBACH, S ;
DUBOIS, RN .
GASTROENTEROLOGY, 1994, 107 (04) :1183-1188
[9]   A GENETIC MODEL FOR COLORECTAL TUMORIGENESIS [J].
FEARON, ER ;
VOGELSTEIN, B .
CELL, 1990, 61 (05) :759-767
[10]   Involvement of integrins alpha(v)beta(3) and alpha(v)beta(5) in ocular neovascular diseases [J].
Friedlander, M ;
Theesfeld, CL ;
Sugita, M ;
Fruttiger, M ;
Thomas, MA ;
Chang, S ;
Cheresh, DA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (18) :9764-9769
123456