Universal Statistics of Incubation Periods and Other Detection Times via Diffusion Models

被引:4
作者
Bakhtin, Yuri [1 ]
机构
[1] Courant Inst Math Sci, New York, NY 10012 USA
基金
美国国家科学基金会;
关键词
Incubation periods; Diffusion; Conditional exit times; First passage times; Right skew; Gumbel distribution; Cumulants; EIGENVALUE; COMPUTE;
D O I
10.1007/s11538-018-00558-w
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We suggest an explanation of typical incubation times statistical features based on the universal behavior of exit times for diffusion models. We give a mathematically rigorous proof of the characteristic right skewness of the incubation time distribution for very general one-dimensional diffusion models. Imposing natural simple conditions on the drift coefficient, we also study these diffusion models under the assumption of noise smallness and show that the limiting exit time distributions in the limit of vanishing noise are Gaussian and Gumbel. Thus, they match the existing data as well as the other existing models do. The character of our models, however, allows us to argue that the features of the exit time distributions that we describe are universal and manifest themselves in various other situations where the times involved can be described as detection or halting times, for example response times studied in psychology.
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页码:1070 / 1088
页数:19
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