Modelling heterozygote balance in forensic DNA profiles

被引：28
作者：
Kelly, Hannah [1 ,2 ]
Bright, Jo-Anne [1 ]
Curran, James M. [2 ]
Buckleton, John [1 ]
机构：
[1] ESR, Auckland, New Zealand
[2] Univ Auckland, Dept Stat, Auckland 1, New Zealand
来源：
FORENSIC SCIENCE INTERNATIONAL-GENETICS | 2012年 / 6卷 / 06期
关键词：
Heterozygous balance; Mixed DNA profiles; LtDNA; DNA thresholds; DNA interpretation; STR; STUTTER;
D O I：
10.1016/j.fsigen.2012.08.002
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
In this paper we investigate the relationship between heterozygous balance (h) and average peak height ((phi) over bar) in a set of Identifiler (TM) data. The mean of heterozygote balance is unaffected by average peak height but the variance about this mean is much lower at high average peak heights. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：729 / 734
页数：6
相关论文
共 29 条
[1]  
[Anonymous], 2005, QUANTILE REGRESSION
[2]  
[Anonymous], 2012, R LANG ENV STAT COMP
[3]   Interpreting low template DNA profiles [J].
Balding, David J. ;
Buckleton, John .
FORENSIC SCIENCE INTERNATIONAL-GENETICS, 2009, 4 (01) :1-10
[4]   Recovery of trace DNA and its application to DNA profiling of shoe insoles [J].
Bright, JA ;
Petricevic, SF .
FORENSIC SCIENCE INTERNATIONAL, 2004, 145 (01) :7-12
[5]   Determination of the variables affecting mixed MiniFiler™ DNA profiles [J].
Bright, Jo-Anne ;
Huizing, Erin ;
Melia, Lisa ;
Buckleton, John .
FORENSIC SCIENCE INTERNATIONAL-GENETICS, 2011, 5 (05) :381-385
[6]   Examination of the variability in mixed DNA profile parameters for the Identifiler™ multiplex [J].
Bright, Jo-Anne ;
Turkington, Jnana ;
Buckleton, John .
FORENSIC SCIENCE INTERNATIONAL-GENETICS, 2010, 4 (02) :111-114
[7]   Characterising stutter in forensic STR multiplexes [J].
Brookes, Clare ;
Bright, Jo-Anne ;
Harbison, SallyAnn ;
Buckleton, John .
FORENSIC SCIENCE INTERNATIONAL-GENETICS, 2012, 6 (01) :58-63
[8]   Is the 2p rule always conservative? [J].
Buckleton, J ;
Triggs, C .
FORENSIC SCIENCE INTERNATIONAL, 2006, 159 (2-3) :206-209
[9]  
Buckleton J.S., 2004, Forensic DNA evidence interpretation
[10]   Analysis and interpretation of mixed forensic stains using DNA STR profiling [J].
Clayton, TM ;
Whitaker, JP ;
Sparkes, R ;
Gill, P .
FORENSIC SCIENCE INTERNATIONAL, 1998, 91 (01) :55-70
123