Pd-Catalyzed Cyclopropanation Reaction of Aliphatic Ketones with Monosubstituted Allyl Reagents

被引：3
作者：
Huang, Jian-Qiang [1 ]
Zhao, Jing-Feng [2 ]
Yang, Zhen [1 ]
Ding, Chang-Hua [1 ]
Hou, Xue-Long [1 ,3 ]
Peng, Xiao-Shui [4 ]
Wong, Henry Nai Ching [3 ,4 ]
机构：
[1] Chinese Acad Sci, State Key Lab Organometall Chem, Shanghai Inst Organ Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China
[2] Pharmaron Beijing Ltd Co, 6 Taihe Rd BDA, Beijing 100176, Peoples R China
[3] Shanghai Inst Organ Chem, Shanghai Hong Kong Joint Lab Chem Synth, 345 Lingling Rd, Shanghai 200032, Peoples R China
[4] Chinese Univ Hong Kong, Dept Chem, Shatin, Hong Kong, Peoples R China
来源：
ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 6卷 / 12期
基金：
中国国家自然科学基金;
关键词：
allylic compounds; cyclopropanation; ketones; palladium; NHCs; KETENE SILYL ACETAL; NUCLEOPHILIC-ATTACK; (PI-ALLYL)PALLADIUM COMPLEXES; ACYCLIC AMIDES; CENTRAL CARBON; ALKYLATION; CONSTRUCTION; MECHANISM; LIGAND; ESTERS;
D O I：
10.1002/ajoc.201700541
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A Pd-catalyzed cyclopropanation reaction with aliphatic ketones as nucleophiles using a modified pyridine-NHC ligand was achieved. The reaction afforded the corresponding cyclopropanes in moderate to good yields with high cyclopropane/allylation selectivity.
引用
收藏
页码：1769 / 1772
页数：4
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