EEG oscillatory states as neuro-phenomenology of consciousness as revealed from patients in vegetative and minimally conscious states

被引:60
作者
Fingelkurts, Alexander A. [1 ]
Fingelkurts, Andrew A. [1 ]
Bagnato, Sergio [2 ,3 ]
Boccagni, Cristina [2 ,3 ]
Galardi, Giuseppe [2 ,3 ]
机构
[1] BM Sci Brain & Mind Technol Res Ctr, FI-02601 Espoo, Finland
[2] Fdn Ist San Raffaele G Giglio, Neurorehabil Unit, Rehabil Dept, Cefalu, PA, Italy
[3] Fdn Ist San Raffaele G Giglio, Neurophysiol Unit, Rehabil Dept, Cefalu, PA, Italy
关键词
Electroencephalogram (EEG); Disorder of consciousness; EEG oscillations; Brain microstates; Awareness; Minimally conscious state (MCS); Vegetative state (VS); Spectral patterns; BRAIN-INJURED PATIENTS; ALPHA-PATTERN COMA; BEHAVIORAL-INHIBITION; ALTERED STATES; THETA BAND; DYNAMICS; SCALE; RECOVERY; TIME; SYNCHRONIZATION;
D O I
10.1016/j.concog.2011.10.004
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
The value of resting electroencephalogram (EEG) in revealing neural constitutes of consciousness (NCC) was examined. We quantified the dynamic repertoire, duration and oscillatory type of EEG microstates in eyes-closed rest in relation to the degree of expression of clinical self-consciousness. For NCC a model was suggested that contrasted normal, severely disturbed state of consciousness and state without consciousness. Patients with disorders of consciousness were used. Results suggested that the repertoire, duration and oscillatory type of EEG microstates in resting condition quantitatively related to the level of consciousness expression in brain-damaged patients and healthy-conscious subjects. Specifically, results demonstrated that (a) decreased number of EEG microstate types was associated with altered states of consciousness, (b) unawareness was associated with the lack of diversity in EEG alpha-rhythmic microstates, and (c) the probability for the occurrence and duration of delta-, theta- and slow-alpha-rhythmic microstates were associated with unawareness, whereas the probability for the occurrence and duration of fast-alpha-rhythmic microstates were associated with consciousness. In conclusion, resting EEG has a potential value in revealing NCC. This work may have implications for clinical care and medical-legal decisions in patients with disorders of consciousness. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:149 / 169
页数:21
相关论文
共 189 条
[1]   Trait anxiety impact on the EEG theta band power changes during appraisal of threatening and pleasant visual stimuli [J].
Aftanas, LI ;
Pavlov, SV ;
Reva, NV ;
Varlamov, AA .
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, 2003, 50 (03) :205-212
[2]   Affective picture processing: event-related synchronization within individually defined human theta band is modulated by valence dimension. [J].
Aftanas, LI ;
Varlamov, AA ;
Pavlov, SV ;
Makhnev, VP ;
Reva, NV .
NEUROSCIENCE LETTERS, 2001, 303 (02) :115-118
[3]   Mental states as macrostates emerging from brain electrical dynamics [J].
Allefeld, Carsten ;
Atmanspacher, Harald ;
Wackermann, Jiri .
CHAOS, 2009, 19 (01)
[4]  
[Anonymous], 2003, The brain's alpha rhythms and the mind
[5]  
[Anonymous], SPEKTRUM NEUROREHABI
[6]  
[Anonymous], EVOLYUTSIONNAYA EPIS
[7]  
[Anonymous], 2004, Mind time
[8]  
[Anonymous], 2001, J NEUROTHER
[9]  
[Anonymous], 2000, A Universe of Consciousness: How Matter Becomes Imagination
[10]  
[Anonymous], FOCUS BRAIN MAPPING