Preparation and antibacterial activity of quaternized chitosan with iodine

被引：28

作者：

Tang, Yang ^{[1
]}

Xie, Linlin ^{[1
]}

Sai, Mingze ^{[1
]}

Xu, Ningning ^{[1
]}

Ding, Derun ^{[1
]}

机构：

[1] Shanghai Univ Engn Sci, Coll Chem & Chem Engn, Shanghai 201620, Peoples R China

来源：

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2015年 / 48卷

关键词：

Chitosan; Quatemization; Iodine; Antibacterial; Iodometric titration; POLYVINYLPYRROLIDONE-IODINE; COMPLEX; DERIVATIVES; DELIVERY; STARCH; CHITIN; SALT; ION;

D O I：

10.1016/j.msec.2014.11.019

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Chitosan (CTS) is a natural polymer with active groups such as -NH2 which can be functionalized to introduce new positively charged N-atoms and protonated amino group for better use. In this study, to improve the stability of iodine, a novel complex (CTS-CTA-I-2) was prepared by mixing N-(2-hydroxy) propyl-3-trimethylammonium chitosan chloride (CTS-CFA) with iodine in ethanol solution. The CTS-CTA-I2 was characterized by Fourier transform infrared spectra (FTIR), Ultraviolet and visible (UV-vis) spectra and thermal gravimetric analysis (TG). Besides, the interaction of iodine with CTS-CTA was also studied. The mole ratio of CTS-CFA with iodine was measured by iodometric titration method and the max mole ratio of CTS-CFA with iodine was 1:133. The antimicrobial activity of CTS, CTS-CTA and CTS-CTS-I-2 complexes was investigated against Escherichia coli and Staphylococcus aureus and the antibacterial property of CTS-CFA-I-2 was superior to CTS-CFA. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：1 / 4

页数：4

共 27 条

[1] Chitosan-based delivery systems for protein therapeutics and antigens [J].

Amidi, Maryam ;

Mastrobattista, Enrico ;

Jiskoot, Wim ;

Hennink, Wim E. .

ADVANCED DRUG DELIVERY REVIEWS, 2010, 62 (01) :59-82

[2] Molecular iodine preconcentration and determination in aqueous samples using poly(vinylpyrrolidone) containing membranes [J].

Bhagat, P. R. ;

Pandey, A. K. ;

Acharya, R. ;

Nair, A. G. C. ;

Rajurkar, N. S. ;

Reddy, A. V. R. .

TALANTA, 2008, 74 (05) :1313-1320

[3] THE USE OF ACTIVE IODINE AS A WATER DISINFECTANT [J].

CHANG, SL .

JOURNAL OF THE AMERICAN PHARMACEUTICAL ASSOCIATION, 1958, 47 (06) :417-423

[4] Study on β-cyclodextrin grafting with chitosan and slow release of its inclusion complex with radioactive iodine [J].

Chen, SP ;

Wang, YT .

JOURNAL OF APPLIED POLYMER SCIENCE, 2001, 82 (10) :2414-2421

[5]

Harley J.P., 2012, ILLUSTRATION MICROBI, P60

[6] Electrospinning of poly(vinyl pyrrolidone)-iodine complex and poly(ethylene oxide)/poly(vinyl pyrrolidone)-iodine complex - a prospective route to antimicrobial wound dressing materials [J].

Ignatova, Milena ;

Manolova, Nevena ;

Rashkov, Iliya .

EUROPEAN POLYMER JOURNAL, 2007, 43 (05) :1609-1623

[7] Flow injection amperometry for the determination of iodate in iodized table salt [J].

Jakmunee, J ;

Grudpan, K .

ANALYTICA CHIMICA ACTA, 2001, 438 (1-2) :299-304

[8] The effect of moist heat treatment on the characteristic of starch-based composite materials coating with chitosan [J].

Lin, Baofeng ;

Du, Yumin ;

Li, Yanming ;

Liang, Xingquan ;

Wang, Xiaoying ;

Deng, Wen ;

Wang, Xiaohui ;

Li, Lei ;

Kennedy, John F. .

CARBOHYDRATE POLYMERS, 2010, 81 (03) :554-559

[9]

Loannis L., 2013, CARBOHYD POLYM, V92, P176

[10] Chitosan-modifications and applications: Opportunities galore [J].

Mourya, V. K. ;

Inamdar, Nama N. .

REACTIVE & FUNCTIONAL POLYMERS, 2008, 68 (06) :1013-1051

← 1 2 3 →