IDENTIFYING ELDERLY WOMEN WITH OSTEOPOROSIS BY SPINAL DUAL X-RAY ABSORPTIOMETRY, CALCANEAL QUANTITATIVE ULTRASOUND AND SPINAL QUANTITATIVE COMPUTED TOMOGRAPHY: A COMPARATIVE STUDY

被引:21
作者
Edelmann-Schaefer, Bianca [1 ]
Berthold, Lars Daniel [2 ]
Stracke, Hilmar [3 ,4 ]
Luehrmann, Petra Maria [1 ,5 ]
Neuhaeuser-Berthold, Monika [1 ]
机构
[1] Univ Giessen, Inst Nutr Sci, D-35390 Giessen, Germany
[2] Hannover Med Sch, Inst Radiol, D-3000 Hannover, Germany
[3] Univ Hosp Giessen, Med Clin & Policlin 3, Giessen, Germany
[4] Marburg GmbH, Giessen, Germany
[5] Univ Educ, Dept Nutr Consumpt & Fash, Schwabisch Gmund, Germany
关键词
Osteoporosis; Diagnosis; Dual x-ray absorptiometry; Quantitative ultrasound; Quantitative computed tomography; T-score; BONE-MINERAL DENSITY; T-SCORE; RISK; BMD; THRESHOLDS; IDENTIFICATION; DISCORDANCE; PREVALENCE; PREDICTION; MANAGEMENT;
D O I
10.1016/j.ultrasmedbio.2010.10.003
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
The ability of spinal dual x-ray absorptiometry (DXA), calcaneal quantitative ultrasound (QUS) and spinal quantitative computed tomography (QCT) to identify women with osteoporosis within the GISELA study was evaluated in 43 women, aged 62-87 years. Osteoporosis was defined as a T-score below or equal to -2.5 using DXA (femoral neck). To determine the performance of each method, the sensitivity, specificity and area under the curve (by means of a receiver operating characteristic [ROC] analysis) were calculated. The median T-scores from the measurements differed significantly (p < 0.0001). DXA (spine) identified 75% of women with osteoporosis; QUS and QCT identified 100%. The specificity was 89% for DXA (spine), 66% for QUS and 29% for QCT. ROC analysis showed that all three methods are qualified to identify women with osteoporosis; however, the different sensitivities and specificities of the methods, as well as the thresholds used for diagnosing osteoporosis have to be considered. (E-mail: monika.neuhaeuser-berthold@ernaehrung.uni-giessen.de) (C) 2011 Published by Elsevier Inc. on behalf of World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码:29 / 36
页数:8
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