Clinical Profile and Hospital Outcome of Children with Severe Acute Kidney Injury in a Developing Country

被引：15

作者：

Esezobor, Christopher Imokhuede ^{[1
,2
]}

Ladapo, Taiwo Augustina ^{[1
,2
]}

Lesi, Foluso Ebun ^{[1
,2
]}

机构：

[1] Univ Lagos, Coll Med, Dept Paediat, Mushin 101014, Lagos State, Nigeria

[2] Univ Lagos, Teaching Hosp, Dept Paediat, Mushin 101014, Lagos State, Nigeria

来源：

JOURNAL OF TROPICAL PEDIATRICS | 2015年 / 61卷 / 01期

关键词：

acute kidney injury; dialysis; gastroenteritis; malaria; sepsis; ACUTE-RENAL-FAILURE; NIGERIAN CHILDREN; MORTALITY;

D O I：

10.1093/tropej/fmu066

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Introduction: In resource-constraint regions of the world, the spectrum of childhood diseases is changing, creating a need to clearly define the epidemiology of severe acute kidney injury (AKI). Methods: Medical records of children aged between 1 month and 17 years with stage 3 AKI in a tertiary hospital were reviewed. Results: Ninety-one children, comprising 63 (69.2%) males and 26 (28.6%) infants, were studied. Majority (75.8%) had stage 3 AKI at the point of hospitalization. Sepsis (41.8%), primary kidney diseases (PKD; 29.7%) and malaria (13.2%) were the most common causes of stage 3 AKI. Twenty-eight (30.8%) children died. Mortality was highest in those with sepsis, less than 5 years old and needing dialysis. Conclusion: Sepsis, PKD and malaria were the most common causes of severe AKI. A third of children with severe AKI died. Mortality was highest in those less than 5 years old, with sepsis and needing dialysis.

引用

页码：54 / 60

页数：7

共 19 条

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