Paraneoplastic neurological syndromes and breast cancer. Regression of paraneoplastic neurological sensorimotor neuropathy in a patient with metastatic breast cancer treated with capecitabine: a case study and mini-review of the literature

被引:17
作者
Minisini, Alessandro M.
Pauletto, Giada
Bergonzi, Paolo
Fasola, Gianpiero
机构
[1] Univ & SM Misericordia Hosp, Dept Med Oncol, I-33100 Udine, Italy
[2] Univ & SM Misericordia Hosp, Dept Neurol, Udine, Italy
关键词
neurological paraneoplastic syndrome; autoantibodies; sensorimotor neuropathy; breast cancer; capecitabine;
D O I
10.1007/s10549-006-9444-0
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Paraneoplastic neurological syndromes are a rare complication of breast cancer. Nevertheless, they may be clinically relevant leading to neurological impairment. Clinicians should be aware that these neurological disorders could even precede the diagnosis of breast cancer. Here we present the case of a female patient with advanced breast cancer who developed paraneoplastic sensorimotor neuropathy. Treatment with capecitabine lead to clinical amelioration. A review of the literature on the paraneoplastic neurological syndromes in breast cancer is also included.
引用
收藏
页码:133 / 138
页数:6
相关论文
共 26 条
[1]  
Altaha Ramin, 2003, Breast J, V9, P417, DOI 10.1046/j.1524-4741.2003.09514.x
[2]   AN ANTINEURONAL AUTOANTIBODY IN PARA-NEOPLASTIC OPSOCLONUS [J].
BUDDESTEFFEN, C ;
ANDERSON, NE ;
ROSENBLUM, MK ;
GRAUS, F ;
FORD, D ;
SYNEK, BJL ;
WRAY, SH ;
POSNER, JB .
ANNALS OF NEUROLOGY, 1988, 23 (05) :528-531
[3]   Paraneoplastic peripheral neuropathy associated with anti-Hu antibodies -: A clinical and electrophysiological study of 20 patients [J].
Camdessanché, JP ;
Antoine, JC ;
Honnorat, J ;
Vial, C ;
Petiot, P ;
Convers, P ;
Michel, D .
BRAIN, 2002, 125 :166-175
[4]   Anti-Yo positive paraneoplastic cerebellar degeneration associated with ovarian carcinoma: Case report and review of the literature [J].
Cao, YM ;
Abbas, J ;
Wu, XL ;
Dooley, J ;
van Amburg, AL .
GYNECOLOGIC ONCOLOGY, 1999, 75 (01) :178-183
[5]   Melanoma-associated retinopathy: does autoimmunity prolong survival? [J].
Chan, C ;
O'Day, J .
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2001, 29 (04) :235-238
[6]  
Corcia P, 2000, REV NEUROL-FRANCE, V156, P1020
[7]  
Dalmau J, 1999, BRAIN PATHOL, V9, P275
[8]   Update on paraneoplastic syndromes [J].
Dropcho, EJ .
CURRENT OPINION IN NEUROLOGY, 2005, 18 (03) :331-336
[9]  
FOLLI F, 2002, ANTIBODIES NEUROLOGI
[10]   Paraneoplastic neurological disorders in breast cancer [J].
Gatti, G ;
Simsek, S ;
Kurne, A ;
Zurrida, S ;
Naninato, P ;
Veronesi, P ;
Frasson, A ;
Millen, E ;
Rososchansky, J ;
Luini, A .
BREAST, 2003, 12 (03) :203-207