In vivomonitoring of carbonic anhydrase expression during the growth of larval zebrafish: a new environment-sensitive fluorophore for responsive turn-on fluorescence

被引:4
|
作者
Chou, Chih-Hung [1 ]
Wu, Chang-Yi [2 ]
Chen, Chun-Lin [2 ]
Zhou, Jun-Qing [2 ]
Kao, Yu-Chen [2 ]
Chen, Hsing-Yin [3 ]
Lin, Po-Chiao [1 ]
机构
[1] Natl Sun Yat Sen Univ, Dept Chem, Kaohsiung 80424, Taiwan
[2] Natl Sun Yat Sen Univ, Dept Biol Sci, Kaohsiung 80424, Taiwan
[3] Kaohsiung Med Univ, Dept Med & Appl Chem, Kaohsiung 80708, Taiwan
关键词
PROTEIN INTERACTIONS;
D O I
10.1039/d0cc03090b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This study monitors the dynamic progress of a newly developed background-free, target responsive strategy; 2,3-dihydroquinolin-4-imine (DQI) that can instantly respond to environmental changes with fluorescence enhancement, revealing a comprehensive platform forin vivofluorescence bioimaging of mebrane-bound carbonic anhydrase II in HeLa cells and its expression during the growth of larval zebrafish.
引用
收藏
页码:11307 / 11310
页数:4
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