Evaluation of clonality in enterococci isolated in Brazil carrying Tn1546-like elements associated with vanA plasmids

被引:12
作者
Palazzo, ICV
Camargo, ILBC
Zanella, RC
Darini, ALC
机构
[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Anal Clin Toxicol & Bromatol, BR-14040903 Ribeirao Preto, SP, Brazil
[2] Inst Adolfo Lutz Registro, Bacteriol Lab, Sao Paulo, Brazil
关键词
enterococci; vancomycin resistance; Tn1546; plasmid DNA;
D O I
10.1111/j.1574-6968.2005.00181.x
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Fifty-one vancomycin-resistant enterococci samples isolated from different geographic regions in Brazil were studied. All the isolates harboured the vanA gene as demonstrated by PCR analysis, and in a majority of strains the gene was associated with a transferable plasmid of 70 kb. A single variant of the prototype Tn1546 associated with common transferable vanA-containing plasmids has spread among the enterococcal strains circulating in Brazil. The VanA element integrity in these enterococci strains and the different pulsed-field gel electrophoresis patterns suggest horizontal transmission of the vancomycin resistance transposon in Brazilian strains.
引用
收藏
页码:29 / 36
页数:8
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